August 30, 2021 to September 3, 2021
University of Innsbruck
Europe/Zurich timezone

【617】Decomposition of the RRx-001 radiosensitizer by low-energy electrons

Sep 3, 2021, 12:45 PM
15m
Room E

Room E

Talk Applied Physics and Plasma Physics Applied Physics and Plasma Physics

Speaker

Mr Farhad Izadi (1. Institute for Ion Physics and Applied Physics, University of Innsbruck)

Description

Electron capture by molecules leads to the formation of transient negative ions, which may dissociate through dissociative electron attachment (DEA). DEA to the 1-bromoacetyl-3,3-dinitroazetidin (RRx-001) molecule in the gas phase has been studied utilizing a crossed electron-molecular beam setup combined with a quadrupole mass spectrometer. RRx-001 has been proposed as a radiosensitizer. We observed 11 fragment anions, which indicate that low-energy electrons with kinetic energies ranging from 0 to 14 eV strongly decompose the molecule. The results indicate efficient formation of NO2– and Br– upon DEA to RRx-001.

Primary authors

Mr Farhad Izadi (1. Institute for Ion Physics and Applied Physics, University of Innsbruck) Mr Eugene Arthur-Baidoo (Institute for Ion Physics and Applied Physics, University of Innsbruck,) Prof. Stephan Denifl (Institute for Ion Physics and Applied Physics, University of Innsbruck, Technikerstrasse 25, 6020 Innsbruck, Austria.)

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