We still see problem at OU. I finally was able to repeat this issue at SLAC.
For a long time, SLAC ran xrootd 5.3.0 from xrootd repo, and we never saw the problem. OU runs xrootd 5.3.1 from OSG 3.5upcoming and saw the problem of accumulating TCP CLOSE_WAIT in short period of time.
Since Oct 28, SLAC switched to use the same very OU use and we saw this problem after 9 days. SLAC has since to switched to xrootd 5.3.1 in EPEL to see if we can repeat the problem