-
Ms Gaia Dellepiane (Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics, University of Bern, Switzerland)6/27/22, 4:30 PMBiophysics, Medical Physics and Soft MatterTalk
Radioisotopes for theranostics are essential for nuclear medicine developments. A research program is ongoing at the 18 MeV Bern medical cyclotron, equipped with a solid target station and a 6 m long Beam Transfer Line ending in a separate bunker. To bombard compressed powder pellets, novel target coins were conceived and realized together with methods to assess the beam energy and the...
Go to contribution page -
Ms Doha Abdelrahman (Adolphe Merkle Institute, University of Fribourg)6/27/22, 4:45 PMBiophysics, Medical Physics and Soft MatterTalk
Directed self-assembly (DSA) of block copolymer is a promising approach to achieve macroscopic ordered nanostructures. Here, we investigate the combined effect of solvent vapour annealing and chemical topographical guiding patterning on the self-assembly and grain size of a 3D diamond-forming triblock terpolymer Polyisoprene-block-polystyrene-block-poly(glycidylmethacrylate) (ISG). The guiding...
Go to contribution page -
Dr Christian Sproncken (Adolphe Merkle Institute, University of Fribourg)6/27/22, 5:00 PMBiophysics, Medical Physics and Soft MatterTalk
The membranes of living cells form excellent barriers, separating the cell contents from the outside environment, while only several nanometers thick and spanning large areas. Inspired by these biological membranes, we present the formation and characterization of amphiphilic block copolymer membranes. We demonstrate that these polymers can form membranes of less than 20 nm in thickness over...
Go to contribution page -
Dr Mathias Sebastian Weyland (Zurich University of Applied Sciences)6/27/22, 5:15 PMBiophysics, Medical Physics and Soft MatterTalk
Within the context of the European Horizon 2020 project ACDC, we intend to develop a probabilistic chemical compiler, to aid the construction of three-dimensional agglomerations of artificial hierarchical cellular constructs. These programmable discrete units offer a wide variety of technical innovations, like a portable biochemical laboratory that e.g. produces macromolecular medicine on...
Go to contribution page -
205. 【905】Interrogating Single Molecule Kinetics of Citrate Synthase with Plasmonic Optical TweezersMrs Edona Karakaçi (1.Adolphe Merkle Institute, University of Fribourg)6/27/22, 5:30 PMBiophysics, Medical Physics and Soft MatterTalk
The work presented here demonstrates that plasmonic optical tweezers can reveal insights into the conformational dynamics of native proteins that so far have not been investigated on a single molecule level. We examined citrate synthase , an enzyme of the Krebs cycle, which consists of two identical subunits with one active site per subunit. Previous studies show that during catalysis, each...
Go to contribution page -
Marian Reincke (University of Fribourg, Adolphe Merkle Institute)6/27/22, 5:45 PMBiophysics, Medical Physics and Soft MatterTalk
Solid state nanopores enable the analysis of single biomolecules in solution. Here we present a simple, in situ method for coating silicon nitride nanopores that addresses three of the main challenges in the field. By adding polymer directly to the recording buffer we were able to i) reduce non-specific interactions of the analyte with the pore; ii) suppress growth of the pore in electrolyte;...
Go to contribution page -
René Iseli (Adolphe Merkle Institute)Biophysics, Medical Physics and Soft MatterTalk
Introducing block copolymer self-assembly using a terblock copolymer and solvent evaporation annealing method. Dissolving the polymer in a volatile and nonvolatile solvents divides the nucleation and growth steps during the microphase separation. Speeding up the process by spin coating and evaporation of the volatile component up to the onset of nucleation and minimizing the nucleation rate...
Go to contribution page
Choose timezone
Your profile timezone: