Jun 25 – 29, 2023
Ole-Johan Dahls Hus
Europe/Oslo timezone

A new nuclear imaging detection technology for total body, flexible and fast SPECT diagnoses.

Jun 29, 2023, 11:40 AM
Simula Auditorium (Ole-Johan Dahls Hus)

Simula Auditorium

Ole-Johan Dahls Hus

Oslo Science Park Gaustadalléen 23B, 0373 Oslo
Oral Detector systems Detector Systems


Michela Marafini


The International Agency for Research on Cancer estimated a 25% risk of tumor incidence in the European population (2018), destined to increase in the coming years. Prevention and early diagnosis remain the fundamental tools, and nuclear imaging plays a pivotal role for noninvasive diagnosis.
One of the most used diagnostic technology is the Single Photon Emission Computed Tomography (SPECT).
While the conventional SPECT detector heads are generally built using collimators coupled to monolithic inorganic crystals, in this contribution we investigate a gamma detector concept that relies on a tungsten metal frame (hive), that serves both as a collimator and as a container for the scintillator segments. The active material has been chosen to be organic scintillators enriched with high-Z elements to profit from the extremely fast scintillation process and a still remarkable photoelectric effect probability.

Thanks to the very short scintillation time of the active material and to the pixellated readout, an incredibly high count-rate capability will be achievable.
The readout system is a custom design tuned for fast scintillation events with an independent channel for each scintillator segment allowing the simultaneous measurement of the gamma arrival time and energy.
This device has the potential of opening the way to a new family of gamma imaging detectors based on organic scintillators combined with 3D printed collimators, allowing for a significant cost reduction while
achieving a beyond state-of-the-art count-rate capability and field of view.
Images from conventional SPECT from patients of Policlinico Umberto I Hospital have been exploited as starting point for a Montecarlo based reconstruction study with the aim of optimizing the detector geometry and of evaluate the achievable performances.
In this contribution, the expected performances of a total body system will be presented together with the results obtained with the first prototypes.

Primary authors

Adalberto Sciubba (INFN e Laboratori Nazionali di Frascati (IT)) Dr Alessio Sarti (Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Via Antonio Scarpa 14, Rome, 00161, Italy) Angelica De Gregorio Angelo Schiavi (Università di Roma "La Sapienza") Dr Annalisa Muscato (Scuola post-laurea in Fisica Medica, Dipartimento di Scienze e Biotecnologie medico-chirurgiche, Sapienza Universita` di Roma, Italy) Antonio Trigilio Dr Daniele Rocco (Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Via Antonio Scarpa 14, Rome, 00161, Italy) Gaia Franciosini (Dipartimento di scienze di base e applicate per l'ingegneria, Sapienza, University of Rome) Giacomo Traini Prof. Giuseppe De Vincentis (Department of Radiological Sciences, Oncology and Anatomo-Pathology, University of Rome, Rome, Sapienza, 00185, Italy) Dr Leonardo Mattiello (Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Via Antonio Scarpa 14, Rome, 00161, Italy) Dr Marco Garbini (Enrico Fermi” Historical Museum of Physics and Study & Research Centre-CREF, Via Panisperna 89a, Rome, 00184, Italy) Marco Magi (Dipartimento di Scienze di Base e Applicate per l’Ingegneria, Sapienza Università di Roma, Italy) Marco Toppi (INFN Section of Rome I, Rome, Italy.) Marta Fischetti (INFN - National Institute for Nuclear Physics) Michela Marafini Micol De Simoni (Ludwig-Maximilians-Universität, Geschwister-Scholl-Platz, 1, Munich, D-80539, Bavaria, Germany) Riccardo Mirabelli Vincenzo Patera (University of Rome Sapienza)

Presentation materials