Jun 13 – 19, 2015
University of Alberta
America/Edmonton timezone
Welcome to the 2015 CAP Congress! / Bienvenue au congrès de l'ACP 2015!

Single-Molecule Microscopy System for Tunable Nanoscale Confinement

Jun 17, 2015, 7:02 PM
CCIS Ground Floor PCL lounge (University of Alberta)

CCIS Ground Floor PCL lounge

University of Alberta

Poster (Student, Not in Competition) / Affiche (Étudiant(e), pas dans la compétition) Medical and Biological Physics / Physique médicale et biologique (DMBP-DPMB) DMBP Poster session, with beer / Session d'affiches DPMB, avec bière


Mr Adriel Arsenault (McGill University)


We present the design and construction of a versatile, open-frame inverted microscope system for wide-field fluorescence and single molecule imaging. The microscope chassis and modular design allow for customization, expansion, and experimental flexibility. We present two components that are included with the microscope which extend its basic capabilities and together create a powerful microscopy system. The first is a piezoelectric controlled Convex Lens-induced Confinement (CLiC) device that provides the system with single-molecule imaging capabilities, and the ability to manipulate molecules at the nanoscale. The CLiC device creates a precise sample-chamber gap that can be adjusted during an experiment to confine molecules or align them within embedded nanostructures. Additionally, a two-color imaging system provides the option of imaging multiple molecular species simultaneously. The flexibility of this microscopy system with its open-framed chassis combined with accessible single-molecule, multi-species imaging technology supports a wide range of new measurements in the health, nanotechnology and materials science research sectors.

Primary author

Mr Adriel Arsenault (McGill University)

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