ICTR-PHE 2016

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Sessions*

Revisiting RBE

Novel strategies to overcome cancer: Tumor cell radiosensitivity modulation

Proffered papers - Physics

Particle therapy (II)

Proffered papers - Detectors and Imaging

Proffered papers - Radiobiology

Lunch & Start-up presentations

European School of Oncology - E. van der Schueren Award

Emerging challenges in combating cancer

Proffered papers -Biology

Modulating response to radiation

Concluding remarks

Radiobiology

Plenary

Nuclear Medicine

New Technologies

Detectors & Imaging

Novel approaches in imaging

ESTRO lecture

Proffered papers- clinical

Particle therapy (I)

Research seminar:Overcoming cancer radioresistance

Winning posters

Panel discussion

Panel discussion

Novel strategies to overcome cancer (I): Immunology-based attacks

Oral poster presentation- Physics/Biology

Proffered papers - Emerging technologies

Novel strategies to overcome cancer (II): Enhancing the ratio between tumor cell killing and normal tissue protection

Panel discussion

GH Fletcher Lecture

EORTC session

Genomics

MEDICIS - PROMED program

Biomolecular mechanisms driving modulation of tumor cell sensitivity

Preclinical models

Panel discussion

Oral poster presentation - Miscellaneous

Oral poster presentation- Clinics

Panel discussion

Oral poster presentation- Detectors and Imaging

Include materials from selected sessions

Contributions*

64Cu-Labeled Folate Radioconjugate for PET Imaging of Folate Receptor-Positive Tumors (in session "Nuclear Medicine")

A clinical protocol for Simultaneous Integrated Boost for proton treatment of Head and Neck carcinoma (in session "Oral poster presentation- Clinics")

A comprehensive omics approach for development of prognostic or predictive biomarkers in squamous cell carcinoma of the head and neck treated with radiation (in session "Radiobiology")

A dose response analysis of the patients treated with Boron Neutron Capture Therapy (BNCT) in Finland in 1999 to 2011 (in session "Proffered papers - Radiobiology")

A Hypercellular Component of Glioblastoma Identified by High b-value Diffusion Weighted Imaging (in session "Oral poster presentation- Clinics")

A novel method to predict a priori the toxicity reduction of a prostate-rectum spacer: Virtual Rectum Spacer (in session "Proffered papers- clinical")

Accuracy of portal dosimetry in hybrid IMRT and VMAT treatment of the prostate (in session "Oral poster presentation- Physics/Biology")

An online beam monitor detector for medical applications of ion beams (in session "Oral poster presentation- Detectors and Imaging")

Are there common signaling pathways among highly radioresistant tumors? The examples of high grade gliomas and sarcomas (in session "Panel discussion")

Assessment tool to quantify and visualize treatment plan robustness regarding patient setup (in session "Oral poster presentation- Clinics")

Balanced checkpoint activation: genomic stability and cell response to radiation (in session "Modulating response to radiation")

Big Data in Radiation Oncology: data gathering, data processing, algorithms and clinical impact (in session "New Technologies")

Biological issues and their clinical implications in proton therapy (in session "Plenary")

Biological stratification in times of highly conformal radiotherapy - status and perspectives (in session "Plenary")

Can we replace high quality simulation CT by simple kV-cone-beam CT images to extract an externally validated radiomics signature? (in session "Proffered papers - Physics")

Carbon ion radiotherapy: do we understand each other? How to compare differentt RBE-weighted dose systems in the clinical setting (in session "Revisiting RBE")

Characterization and test beam results of a LaBr3 Compton Telescope for treatment monitoring (in session "Proffered papers - Emerging technologies")

CHIC – A Multi-scale Modelling Platform for in-silico Oncology (in session "Oral poster presentation- Detectors and Imaging")

Clinical trials for carbon-ion radiotherapy in Japan (in session "Panel discussion")

Clinical validation of the M5L lung Computer-Assisted Detection system (in session "Oral poster presentation - Miscellaneous")

Commissioning of a Compton camera for ion beam range verification via prompt gamma detection using low-energy and clinical particle beams (in session "Proffered papers - Detectors and Imaging")

Comparison of Arterial Input Functions by Magnitude and Phase Signal Measurement in DCE MRI of brain cancer patients (in session "Oral poster presentation- Detectors and Imaging")

Conceptual Design report for OpenMED (in session "Panel discussion")

Contribution of direct and bystander effects to therapeutic efficacy of alpha-RIT using ²¹²Pb-labeled mAbs (in session "Nuclear Medicine")

Correlation of Particle Traversals with Clonogenic Survival Using Cell-Fluorescent Ion Track Hybrid Detector (in session "Radiobiology")

Current and future strategies developed at Paul Scherrer Institute (in session "Panel discussion")

Current status of particle therapy at CNAO (in session "Particle therapy (II)")

Current status of particle therapy in The Netherlands (in session "Particle therapy (II)")

Data from the EORTC Cancer Survivorship Task Force (in session "EORTC session")

Design of electronic data processing system for radiotherapy study: lessons learned from VoxTox (in session "Oral poster presentation- Clinics")

Determining cell radiosensitivity using assays in ex vivo irradiated tumour specimens (in session "Biomolecular mechanisms driving modulation of tumor cell sensitivity")

Development of a High Resolution Module for PET scanners (in session "Detectors & Imaging")

Development of a radioguided surgery technique with beta- decays in brain tumor resection (in session "Detectors & Imaging")

Differential cross sections measurements for hadrontherapy: 50 MeV/n 12C reactions on H, C, Al, O and natTi targets (in session "Oral poster presentation - Miscellaneous")

Disruption of telomere equilibrium sensitises human cancer cells to DNA repair inhibition and radiation (in session "Radiobiology")

Distributed learning: predictive models based on data from multiple hospitals without data leaving the hospital (in session "Oral poster presentation- Clinics")

DoPET: an in-treatment monitoring system for particle therapy (in session "Proffered papers - Detectors and Imaging")

Dosimetry of ultra high dose rate irradiation for studies on the biological effect induced in normal brain and GBM (in session "New Technologies")

Early variation of FDG-PET radiomics features in NSCLC is related to overall survival - the “delta radiomics” concept (in session "Nuclear Medicine")

Emerging challenges in combating cancer (in session "Emerging challenges in combating cancer")

Evaluation of long-term effects of synchrotron-generated microbeams on rat hippocampal neurogenesis (in session "New Technologies")

Experimental dosimetric comparisons of protons, helium, carbon and oxygen ion beams (in session "Proffered papers - Physics")

Expert knowledge and data-driven Bayesian Networks to predict post-RT dyspnea and 2-year survival (in session "New Technologies")

Factors of radioresistance in prostate cancer (in session "Research seminar:Overcoming cancer radioresistance")

Fast Beam Profile Monitors for Microbeam Radiation Therapy (in session "Detectors & Imaging")

Fast calibration of the range of Carbon ionswith in-beam PET of Boron-8 nuclei (in session "Oral poster presentation- Detectors and Imaging")

First clinical application of a prompt gamma based in vivo proton range verification using a knife-edge slit camera (in session "Detectors & Imaging")

Focal adhesion signaling and therapy resistance in cancer (in session "Modulating response to radiation")

Further Development of Spinal Tissue Radiotherapy Re-treatment Modelling, with inclusion of Hadrontherapy (in session "Proffered papers- clinical")

Geant4 coupled with Comsol heat transfer simulations to determine correction factors of a novel micro-calorimeter (in session "New Technologies")

Genetic and pharmacological inhibition of autophagy after irradiation (in session "Biomolecular mechanisms driving modulation of tumor cell sensitivity")

Geometrical interpretation of TOF PET raw data in commercial PET-CT scanner for SNR optimization (in session "Proffered papers - Emerging technologies")

GPU based iterative CBCT for prospective motion compensated algorithm for radiation therapy (in session "Oral poster presentation- Detectors and Imaging")

Hadron minibeam radiation therapy: feasibility study at the Heidelberg IonBeam Therapy Center (HIT) (in session "New Technologies")

HIF-related therapeutic windows (in session "Panel discussion")

High Performance Preclinical Irradiation Through Optimized Dual Focal Spot Dose Painting and Online Virtual Isocenter Radiation Field Targeting (in session "Preclinical models")

How emerging trends in basic research & technology will shape clinical research? (in session "ESTRO lecture")

How to produce scandium-44 and scandium-43 efficiently? (in session "Nuclear Medicine")

Human Sphingolipid Biomarkers of Single Dose Radiotherapy: A Clinical trial (in session "Research seminar:Overcoming cancer radioresistance")

Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma (in session "Panel discussion")

Imaging for online control of particle therapy (in session "Detectors & Imaging")

Implementation of an analytical solution to lateral dose prediction in a proton therapy treatment planning system (in session "Proffered papers - Physics")

In-vitro RBE (in session "Revisiting RBE")

Inhibiting the actions of cathepsin L effects both tumour initiation and metastasis formation (in session "Proffered papers -Biology")

Integration of economic data in clinical trials (in session "Particle therapy (II)")

Investigating the impact of a variable RBE on proton dose fractionation across an actively scanned spread-out Bragg peak (in session "Radiobiology")

Investigation of the use of inhomogeneous fractional dose distributions in IMPT to improve the therapeutic index (in session "Oral poster presentation- Physics/Biology")

Is Distributed learning the solution for Rapid Learning Health Care? (in session "Plenary")

Is dual energy CT the next standard imaging modality for radiotherapy? (in session "Novel approaches in imaging")

J-PET: a novel TOF-PET scanner based on plastic scintillators (in session "Detectors & Imaging")

Lessons from translational research in EORTC Glioma trials (in session "EORTC session")

Local Tumor Flare Following Radiosurgery and Ipilimumab (Ipi) for Melanoma Brain Metastases: Increased Immune Response? (in session "Proffered papers- clinical")

Macrophage reprogramming for anticancer therapy (in session "Modulating response to radiation")

Magnetic resonance temperature imaging in clinical hyperthermia: past experience and prospects (in session "Emerging challenges in combating cancer")

Main challenges in adaptive radiotherapy (in session "Panel discussion")

Manufacturing and Nuclear Medicine Applications of the Novel Isotope Sn-117m (in session "Nuclear Medicine")

Measurement of Acoustic Emissions Generated by a Pulsed Proton Beam from a Hospital-Based Clinical Cyclotron (in session "Detectors & Imaging")

Measurements and simulations of in-phantom neutron dose from a proton pencil beam (in session "Oral poster presentation- Detectors and Imaging")

Measurements of Reactive Oxygen Species production induced by Gold Nanoparticles in Radiotherapy protoco (in session "Oral poster presentation- Physics/Biology")

MedAustron - status and vision (in session "Particle therapy (I)")

Medical isotope production at TRIUMF and future collaboration with MEDICIS-PROMED (in session "MEDICIS - PROMED program")

MEDICIS-PROMED : a ITN Marie-Curie network on nuclear medicine and 11C-based hadron-therapy (in session "MEDICIS - PROMED program")

MEDICIS-PROMED: MEDICIS-Produced Radioisotope Beams for Medicine an Innovative Training Network (in session "MEDICIS - PROMED program")

Metal implanted multi-functional nanovectors for targeted radiotherapy and diagnostics of cancer (in session "Oral poster presentation - Miscellaneous")

Microbeam Radiation Therapy (MRT): achievements and future perspectives (in session "Oral poster presentation- Physics/Biology")

Microtubule-stabilizing agents with inhibitors of angiogenesis to overcome resistance (in session "Panel discussion")

Modeling the effect of symmetrical division of cancer stem cells on tumour response to radiation (in session "Proffered papers - Radiobiology")

Molecular imaging for theranostics (in session "Nuclear Medicine")

MRI for external beam radiotherapy guidance (in session "New Technologies")

MRI Guided Proton Therapy: pencil beam scanning in an MRI fringe field (in session "New Technologies")

Multimodal approach to assess tumour vasculature and potential treatment effect (in session "Panel discussion")

Multimodality Precision Medicine (in session "GH Fletcher Lecture")

Nanoparticle Enhanced MRI-Guided Radiation Therapy: Final proof of concept before phase I trial (in session "New Technologies")

NanoxTM: A new multiscale theoretical framework to predict cell survival in the context of particle therapy (in session "Oral poster presentation- Physics/Biology")

New hypoxia probe development based on mass spectrometry (in session "Novel approaches in imaging")

New Results with Monolithic Scintillators for Time-of-Flight PET (in session "Detectors & Imaging")

Novel anti-tumor agents targeting cell membrane (in session "Novel strategies to overcome cancer: Tumor cell radiosensitivity modulation")

ODSH as a countermeasure for radiation-induced thrombocytopenia: Dosimetric studies (in session "Oral poster presentation- Physics/Biology")

Oncolytic viruses (in session "Novel strategies to overcome cancer (I): Immunology-based attacks")

Oncometabolite lactate promotes tumour growth (in session "Biomolecular mechanisms driving modulation of tumor cell sensitivity")

OPENMED: Topics, Issues and Wishes (in session "Panel discussion")

Optimizing prostate cancer irradiation: from technology to fractionation (in session "Panel discussion")

Orthotopic tumor models for glioma and NSCLC (in session "Preclinical models")

Particle therapy centre in Shanghai (in session "Particle therapy (I)")

Pelvic tumor irradiation: new tools to reduce toxicity: from technology to drugs (in session "Novel strategies to overcome cancer (II): Enhancing the ratio between tumor cell killing and normal tissue protection")

Physics and RBE (in session "Revisiting RBE")

Plerixafor Improves Local Control and Reduces Metastases in Cervical Cancer Treated with Radiotherapy and Chemotherapy (in session "Proffered papers -Biology")

Predictive Biomarkers for Improving Radiation Therapy (in session "Proffered papers - Radiobiology")

Prompt Gamma-ray Timing experiment during different modalities of proton beam delivery (in session "Proffered papers - Detectors and Imaging")

Proton Minibeam Radiation Therapy (pMBRT): implementation at a clinical center (in session "Oral poster presentation- Physics/Biology")

Proton Radiation Therapy: Current Status at Massachusetts General Hospital (in session "Particle therapy (I)")

Public talk - Sound for Health - Domenico Vicinanza

Quantitative Theranostics in Nuclear Medicine (in session "Nuclear Medicine")

Quantum dots imaging tests on SPAD for nanodosimetric applications (in session "Radiobiology")

Radiation induced DNA damage in human uveal melanoma cells (in session "Radiobiology")

Radiation treatment monitoring using multifunctional imaging in prostate tumour xenografts (in session "Proffered papers -Biology")

Radiolabeled Acridine Orange (AO) Derivatives as DNA-Targeted Probes for Auger Therapy (in session "Nuclear Medicine")

Radiomics in Liquid Biopsies (in session "Genomics")

Radiotherapy and the immunocytokine L19-IL2: a perfect match for an abscopal effect with long-lasting memory (in session "Novel strategies to overcome cancer (I): Immunology-based attacks")

Radiotherapy quality assurance platform of the EORTC (in session "EORTC session")

Radiotherapy quality assurance platform of the EORTC (in session "EORTC session")

Range Verification with Ionoacoustics: simulations and measurements at a clinical proton synchro-cyclotron (in session "Detectors & Imaging")

Recurrent glioblastoma multiforme – targeted alpha therapy with 213Bi-DOTA-Substance P (in session "MEDICIS - PROMED program")

Response-based Bayesian Network Approaches for Adaptive Radiotherapy of Non-Small Cell Lung Cancer (NSCLC) (in session "Proffered papers- clinical")

Robustness and reliability of PET-based identification and quantification of tumor hypoxia, using simple static or more complex scan acquisitions (in session "Proffered papers -Biology")

Role of the CERN International Strategy Committee in the LEIR initiative: Biology (in session "Panel discussion")

RSI: A genomic signature of radiosensitivity (in session "Genomics")

Short-lived Positron Emitters in Beam-on PET ImagingDuring Proton Therapy (in session "Proffered papers - Detectors and Imaging")

Simulation of cell survival for proton broad and minibeam radiotherapy with hexagonal and square minibeam alignment (in session "Oral poster presentation- Physics/Biology")

Single particle detection for spectroscopic CT and tracking in hadron therapy using Medipix chips (in session "Plenary")

Small Large Momentum Acceptance Gantries for Proton and Carbon Cancer Therapy (in session "Proffered papers - Emerging technologies")

Status of the CaLIPSO High-Resolution PET Project (in session "Oral poster presentation - Miscellaneous")

Stroma mediated wound healing signals and cell response to radiation (in session "Novel strategies to overcome cancer: Tumor cell radiosensitivity modulation")

Study of the radiation produced by therapeutic He, C and O ion beams impinging on a PMMA target (in session "Proffered papers - Detectors and Imaging")

Studying radiotherapy resistance of BRCA1-mutated mammary tumors (in session "Preclinical models")

Synergy of radiotherapy and cancer vaccines in HPV-positive tumors (in session "Novel strategies to overcome cancer (I): Immunology-based attacks")

Synergy of targeted agents and radiotherapy (in session "EORTC session")

Tackling Phenotypic Diversity to Increase Cures (in session "European School of Oncology - E. van der Schueren Award")

Targeted Radionuclide Therapy with 161Tb: Investigation of Anti-Tumor Effects and Undesired Side Effects (in session "Proffered papers - Radiobiology")

Targeted Treatment for the Non- Small Cell Lung Cancer (in session "Emerging challenges in combating cancer")

Targeting NOTCH pathway in Glioblastoma (in session "Research seminar:Overcoming cancer radioresistance")

Targeting tumor heterogeneity (in session "Novel strategies to overcome cancer: Tumor cell radiosensitivity modulation")

Technological advancement in radiation oncology (in session "Panel discussion")

The Biology of Single Dose Radiotherapy (in session "Panel discussion")

The effect of fractionated administration of thalidomide at γ-ray irradiation on tumor response and lung metastasis (in session "Proffered papers - Radiobiology")

The GEMPIX detector for energy deposition measurements in Hadrontherapy (in session "Oral poster presentation- Detectors and Imaging")

The Malthus Project - updated predictions of national radiotherapy demand to 2030 (in session "Oral poster presentation - Miscellaneous")

The relationship between absorbed dose and DNA Damage in Lymphocytes after radionuclide therapy (in session "Proffered papers - Radiobiology")

The relevance of DNA damage clustering on the nanometer and micrometer scale for the quantitative prediction of radiation effects (in session "Radiobiology")

The role of adipose stromal cells for reversal of radiation fibrosis (in session "Oral poster presentation- Physics/Biology")

The role of functional imaging for radiation oncology – The whole translational chain from animals to clinics (in session "Novel approaches in imaging")

The search for genetic predictors of radiotherapy response (in session "Genomics")

The symbiosis of science of radiation biology with immunology: Impact on basic and translational research (in session "Radiobiology")

The use of 149Tb and 152Tb in preclinical investigations: an update on its mass separation and subsequent application for imaging and therapy (in session "Oral poster presentation- Clinics")

The use of radiobiological TCP and NTCP models to validate the dose calculation algorithm and readjust the prescribed dose (in session "Oral poster presentation - Miscellaneous")

Towards a new type of irradiation (in session "Novel strategies to overcome cancer (II): Enhancing the ratio between tumor cell killing and normal tissue protection")

Towards analytic dose calculation for MR guided particle beam therapy (in session "Proffered papers - Physics")

Treatment of moving targets with active scanning carbon ion beams (in session "Oral poster presentation- Clinics")

Treatment outcome in patients treated with single-dose irradiation (SDRT) for oligometastatic disease (in session "Novel strategies to overcome cancer (II): Enhancing the ratio between tumor cell killing and normal tissue protection")

Trials in Germany (in session "Panel discussion")

Trials in USA (in session "Panel discussion")

Tuning of a 4D ML reconstruction strategy for treatment verification in ion beam radiotherapy (in session "Oral poster presentation - Miscellaneous")

Urethra-sparing SBRT for prostate cancer: dosimetric optimization with VMAT vs. IMRT and the learning curve effect (in session "Proffered papers- clinical")

Utilizing CBCT data for dose calculation in adaptive IMPT (in session "Proffered papers - Physics")

Variable RBE in proton therapy: comparison of model predictions and their impact on clinical-like cranial lesions (in session "Proffered papers -Biology")

Vascular disrupting agents: a new avenue of research (in session "Panel discussion")

Water based 3D optical dose imaging for particle therapy (in session "Proffered papers - Emerging technologies")

Welcome address and opening

What are the Dominant Radiobiological Mechanisms at Play in Stereotactic Radiotherapy? (in session "Radiobiology")

X-Ray Phase contrast micro-imaging in neuroscience (in session "Proffered papers - Emerging technologies")

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Events scheduled on*

2/15/16

2/16/16

2/17/16

2/18/16

2/19/16

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