12–17 Jun 2016
University of Ottawa
America/Toronto timezone
Welcome to the 2016 CAP Congress! / Bienvenue au congrès de l'ACP 2016!

Differential dynamic microscopy studies of collective cell dynamics

15 Jun 2016, 14:15
30m
Colonel By B012 (University of Ottawa)

Colonel By B012

University of Ottawa

Invited Speaker / Conférencier invité Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB) W2-1 Biomechanics and Fluid Dynamics (DPMB) / Biomécanique et dynamique des fluides (DPMB)

Speaker

James L. Harden (University of Ottawa)

Description

We discuss the use of a recently developed microscopy technique, differential dynamic microscopy (DDM), for studying the collective dynamics of two dimensional assemblies of living cells. DDM is a Fourier-space image analysis method that allows one to obtain the equivalent of multi-angle dynamic light scattering data using an ordinary white-light microscopy set-up and a digital video camera. The dynamical information obtained in a DMM experiment is a direct probe of collective cell motion on a range of length and time scales. As such, DMM measurements of cell dynamics are complimentary to direct cell tracking and PIV methods. We illustrate this approach with examples of motile populations of cell at different densities on model substrates.

Primary authors

Fabio Giavazzi (Universitá degli Studi di Milano) James L. Harden (University of Ottawa) Rahil Golipour (University of Ottawa) Roberto Cerbino (Universitá degli Studi di Milano)

Presentation materials

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