Conveners
M3-6 Computational Biophysics: Methods and Concepts (DPMB) / Biophysique numérique : méthodes et concepts (DPMB)
- Francis Lin (University of Manitoba)
Prof.
Sidhartha Goyal
(Univ of Toronto)
13/06/2016, 15:45
Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)
Invited Speaker / Conférencier invité
Much of complex biology results from interactions among a large number of individually simpler elements. Blood regeneration is no different. About 100 billion new blood cells are made everyday from a much smaller yet a large population of diverse stem cell population. I will present a phenomenological model of blood regeneration, which provides a framework to understand large variation (~3...
Apichart Linhananta
(Lakehead University)
13/06/2016, 16:15
Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)
Oral (Non-Student) / orale (non-étudiant)
Research has established a strong link between symptoms of Alzheimer's disease (AD) to 36-43 amino acid residues peptides, called the amyloid beta (A$\beta$) peptides. Patients with AD are usually diagnosed with aggregates of A$\beta$ peptides, also called plaques, which can be as large as several $\mu$m. The structures of the plaques display a wide variety of polymorphisms that depends on the...
Stefan Wallin
(Memorial University of Newfoundland)
13/06/2016, 16:30
Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)
Invited Speaker / Conférencier invité
The traditional view holds that proteins fold into essentially unique and stable 3-dimensional structures which, in turn, determine their biological functions. Evidence is mounting, however, for a pervasive role of large-scale conformational changes for how proteins carry out their functions. Examples include the ability of some proteins to switch between entirely different folded structures,...
Vincent Binette
(Université de Montréal)
13/06/2016, 17:00
Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB)
Oral (Student, Not in Competition) / Orale (Étudiant(e), pas dans la compétition)
The Huntingtin protein has drawn considerable attention as its aggregation into amyloid fibrils is related to the Huntington disease, a neurodegenerative disease characterized by motor and emotional dysfunctonalities and the loss of cognitive functions. Of its 3000 plus residues, attention has focused mostly on the first exon of Huntingtin, composed of a amphipatic region of 17 amino acids...