Conveners
M3-4 Medical Imaging (DPMB) | Imagerie médicale (DPMB)
- Luc Beaulieu (Université Laval)
Blood Oxygen Level Dependent functional Magnetic Resonance Imaging (BOLD-fMRI) is a powerful tool to measure brain activity non-invasively. Over the past 25 years, it has become widely used in neuroscience research. However, BOLD does not measure neurons directly, but instead results from a complex interplay of vascular and metabolic processes, termed the ‘hemodynamic response’. Therefore,...
There are important evidences that spontaneous fluctuations of the brain are sustained by a structural architecture of axonal fiber bundles. As recently suggested, this well-defined fiber distribution could be highly informative to understand the underlying principles of spontaneous fluctuations as well as to infer the functional connectivity patterns of the brain. Various models have been...
Interaction vertex imaging in an imaging method relying on detection of secondary particles created by beam interactions in the target. This method is believed to be viable for tracking dose deposition in patients undergoing heavy-ion radiotherapy. We investigated the impact of two key reconstruction algorithms on image accuracy: a single-particle-and-beam method, as proposed by previous work,...
The measurement of brain axon diameter distributions is important in neuroscience, because axon diameter is directly proportional to nerve conduction velocity. Recent studies indicate possible changes in axon diameter distributions associated with diseases such as Alzheimer’s disease, autism, diabetes, dyslexia, fetal alcohol spectrum disorders and schizophrenia. The methods currently...
Optoacoustic (OA) imaging is being investigated as a non-invasive technique to characterize tissue microvasculature. The technique involves exposing tissues to nanosecond pulsed near infrared laser light. The optical energy is absorbed by tissue chromophores (eg hemoglobin) and converted into heat, leading to thermoelastic expansion, and the production of acoustic waves. The generated acoustic...
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