3-8 September 2017
The Open University, Milton Keynes, UK.
Europe/London timezone

Development of a range telescope for proton CT

6 Sep 2017, 11:00
20m
Berrill Lecture Theatre (OU) ()

Berrill Lecture Theatre (OU)

The Open University, Walton Hall, Milton Keynes, MK7 6AA

Speaker

Michela Esposito (University of Lincoln)

Description

The use of Proton Therapy for cancer treatment demands new and more accurate imaging modalities for treatment planning, based on direct measurements of tissue stopping power instead of tissue density (as in conventional X-ray Computed Tomography) to reduce the errors in converting the latter quantity into the former [1]. The expected benefits of proton CT (pCT) for treatment planning in Proton Radiotherapy are producing great interest worldwide to develop instruments for clinical-quality pCT.

In 2012 a new UK-based collaboration, named PRaVDA (Proton Radiotherapy Verifications and Dosimetry Applications), was formed to develop a fully solid state instrument for pCT [2]. The PRaVDA pCT system, based on Silicon Strip Detectors (SSDs), comprises two sets of trackers to track protons through the patient [3] and a solid-state Range Telescope (RT) to measure the individual proton’s residual energy.
Design, assembly, track reconstruction techniques, range calibration and resolution will be shown for the PRaVDA RT. Experimental results obtained at the iThemba LABS clinical proton facility will also be reported together with preliminary results on pCT reconstruction of a test object with tissue substitute inserts.

[1] M.Yang et al. 2012,“Comprehensive analysis of proton range uncertainties related to patient stopping-power-ratio estimation using the stoichiometric calibration,” Physics in Medicine and Biology, vol. 57, no. 13, p. 4095.

[2] G. Poludniowski et al 2015, “Proton radiography and tomography with application to proton therapy”, The British Journal of Radiology 88:1053

[3] J. T. Taylor et al 2016, “An experimental demonstration of a new type of proton computed tomography using a novel silicon tracking detector” Med Phys. 2016, Nov;43(11):6129

Primary author

Michela Esposito (University of Lincoln)

Co-authors

Chris Waltham (University of Lincoln) Dr Jon Taylor (University of Liverpool (GB)) Tony Price (University of Birmingham (GB)) Ben Phoenix (University of Birmingham) Sam Manger (University of Warwick) Gavin Poludniowski (Karolinska University Hospital) Philip Patrick Allport (University of Birmingham (UK)) Philip Evans (University of Surrey) Stuart Green (University Hospital Birmingham) David Parker (University of Birmingham) Spyros Manolopoulos (University Hospitals Coventry and Warwickshire NHS Trust) Jaime Nieto-Camero (iThemba LABS) Julyan Symons (iThemba LABS) Nigel Allinson (University of Lincoln)

Presentation Materials