Sep 12 – 17, 2021
University of Birmingham
Europe/London timezone

Proton-range verification in proton radiation therapy using PET

Sep 16, 2021, 10:33 AM
1m
Teaching and Learning Building (University of Birmingham)

Teaching and Learning Building

University of Birmingham

Edgbaston Campus University of Birmingham B15 2TT UK
poster Medical Applications of Position Sensitive Detectors Poster Session 5 (Gas-based Detectors; Medical Applications of Position Sensitive Detectors)

Speaker

Mr Kyle Klein (Department of Physics University of Texas at Austin Austin, TX 78712, USA)

Description

We will report first performance results for a prototype PET system designed for proton rage verification in proton therapy. This prototype will later be evaluated with phantoms and animals at the proton therapy center of MD Anderson Cancer Centre in Houston, Texas, USA.
The PET system consists of two detector module assemblies in the shape of angular sections of a cylinder with an inner diameter of 325 mm and axial length 105 mm. The two angular sections cover 99 degrees each. Because of the partial angular coverage, optimization the time resolution is essential in this application. Each PET detector module consists of an 8x8 LYSO array with 3x3x15 mm3 pixels in one-to-one coupling to one Hamamatsu MPPC array S14161-3050HS-08 with 3x3 mm2 pixels. The readout electronics is developed by PETsys Electronics and is based on the PETsys TOFPET2 ASIC. The complete PET system will has 96 detector modules and 6144 electronic readout channels. The interface to the DAQ computer is based on a DAQ module using the PXI express bus, and receiving data from the front-end part through two optical links at 6 Gbit/s.
A Clock&Trigger module located near the detectors will distribute clock signals and allow selecting system wide coincidence events selection in the front end firmware. The complete readout can be divided in a configurable number of trigger regions, and events without a coincidence partner in a different trigger region will not be transmitted to the DAQ computer. This will reduce the data rate to the computer by about one order of magnitude.
We will also report the results of a study of radiation damage to the detectors in this application. The study is based on Geant4 simulation.

email stefaan.tavernier@petsyselectronics.com
Your name Stefaan Tavernier
Nationality Belgian
Title Prof
Institute PETsys Electronics S. A., Portugal

Primary authors

Dr Narayan Sahoo (UT MD Anderson Proton Therapy Center, Houston, USA) Dr Andrei Mozorov (LIP and Departamento de Física, Universidade de Coimbra, Portugal) Prof. Stefaan Tavernier (Vrije Universiteit Brussel (BE)) Dr Carlos Leong (PETsys Electronics S. A., Portugal) Mr Christopher Layden (Department of Physics University of Texas at Austin Austin, TX 78712, USA) Dr David R. Grosshans (UT MD Anderson Proton Therapy Center, Houston, USA) Dr Falk Poenisch (UT MD Anderson Proton Therapy Center, Houston, USA) Dr Francisco Caramelo (ICNAS, Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal) Dr Hugo Simões (LIP and Departamento de Física, Universidade de Coimbra, Portugal) Prof. Joao Varela (PETsys Electronics S. A., Portugal) Dr Jose Carlos Rasteiro Da Silva (PETsys Electronics S. A., Portugal) Dr Jose Sampaio (LIP and FCUL- Faculdade de Ciências, Universidade de Lisboa, Portugal) Prof. Karol Lang (Department of Physics University of Texas at Austin Austin, TX 78712, USA) Mr Kyle Klein (Department of Physics University of Texas at Austin Austin, TX 78712, USA) Dr Luis Ferramacho (PETsys Electronics S. A., Portugal) Mr Marek Proga (Department of Physics University of Texas at Austin Austin, TX 78712, USA) Dr Margarida N Simões (LIP and Departamento de Física, Universidade de Coimbra, Portugal) Dr Miguel Silveira (PETsys Electronics S. A., Portugal) Prof. Nuno Ferreira (ICNAS, Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal) Dr Patrícia Gonçalves (LIP and IST-Instituto Superior Técnico, Universidade de Lisboa, Portugal) Prof. Paulo Crespo (LIP and Departamento de Física, Universidade de Coimbra, Portugal) Dr Ricardo Bugalho (PETsys Electronics S. A., Portugal) Mr Rui Silva (PETsys Electronics S. A., Portugal) Mr William Matava (Department of Physics University of Texas at Austin Austin, TX 78712, USA)

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