Located at the geographic hub of the United States, St. Louis is easily accessible via plane, train and automobile.
By Train: Amtrak
The trains run daily from stations located in the St. Louis suburb of Kirkwood and at the Gateway Transportation Center located on South 15th Street. Along with Amtrak the Gateway Transportation Center serves Greyhound and Burlington Trailways interstate buses and is conveniently located one block from a MetroLink Light Rail Station and Historic St. Louis Union Station.
If you’re driving to St. Louis with your own wheels, our easy-to-use network of Interstate highways makes it a short drive to local attractions. From the east, I-70, I-64 and I-55 head west across the Mississippi River and into downtown St. Louis. I-70 runs north of downtown past the airport and west through Missouri. I-55 turns south past the Anheuser-Busch brewery and continues through southeastern Missouri. I-64, which the locals call Highway 40, continues west through St. Louis, past Forest Park to the Missouri River. I-44 begins in downtown St. Louis and runs southwest along the former path of Route 66 to Springfield, Missouri.
Directions to the Danforth Campus of Washington University can be found here.