Speaker
Description
Magnetic nanoparticles (NPs), especially SPIO nanoparticles, have long been used as MRI
(Magnetic Resonance Imaging) contrast agents and as advantageous nanoplatforms for drug
delivery, taking advantage of their unique magnetic properties and ability to function at the
molecular and cellular level. In our centre smart design and development of SPIO
nanoparticles in mild conditions with desired physico-chemical properties (size, composition,
surface modification, magnetization, relaxivity, biocompatibility, etc.) have been performed
to fulfil desired bioapplication. In this lecture the most promising results will be presented and
consequently discussed advanced in vitro and in vivo MRI application of such prepared SPIO
nanomaterials or nanocomposites. The particular attention will be devoted to labeling and
MRI detection of stem cells, and potential clinical application of maghemite/bentonite
nanocomposite as an per-oral contrast agent.
