In this talk, we reviewed several coherent diffractive processes with nuclear targets. They included soft hadron-nucleus diffraction, hard inclusive diffraction in Deep Inelastic Scattering (DIS) on nuclear targets and hard diffraction in proton-nucleus scattering. We discussed the leading twist theory of nuclear shadowing [1,2,3,4] and presented predictions for usual and diffractive nuclear parton distribution functions [5]. We presented a novel method for the calculation of hard coherent proton-nucleus diffraction [6] using the leading twist theory of nuclear shadowing. We discussed the novel dramatic prediction that soft multiple interactions lead to very large factorization breaking in hard coherent pA diffraction. We compared hard and e.m. mechanisms of hard coherent diffractive production of two jets in pA scattering. We observed that: - For heavy nuclei (Pb-208) at the LHC, hard diffraction is suppressed compared to the e.m. machanism; - For lighter nuclei (Ca-40), hard diffraction is compatible to the e.m. machanism for the production of quark and gluon jets; hard diffraction is suppressed compared to the e.m. machanism for heavy-quark-jets. This suggests the following experimental strategies: - The use of heavy nuclei would allow to cleanly study the $\gamma p$ interaction; - The use of lighter nuclei would allow to study factorization breaking in nuclear diffractive PDFs; - In the same kinematics, a comparison of diffractive dijet production to heavy-quark-jet production would probe nuclear diffractive gluon PDF. References [1] V. Guzey, M. Strikman, hep-ph/0507310 [1] L. Frankfurt, M. Strikman, Eur. Phys. J. A 5 (1999) 293 [2] L. Frankfurt, V. Guzey, M. Strikman, J. Phys. G 27 (2001) R23 [3] L. Frankfurt, V. Guzey, M. McDermott, M. Strikman, JHEP 02 (2002) 27 [4] L. Frankfurt, V. Guzey, M. Strikman, Phys. Rev. D 71 (2005) 054001 [5] L. Frankfurt, V.Guzey , M. Strikman, Phys. Lett. B 586 (2004) 41 [6] V. Guzey, M. Strikman, hep-ph/0507310