Conveners
M4-2 MR and PET Imaging - Part 2 (DPMB) / Imagerie RM et TEP - Partie 2 (DPMB)
- Emily Heath
The main advantage of hybrid PET-MR imaging systems is the ability to correlate anatomical with metabolic information directly. The bulk of commercially available PET-MR systems are quite large and expensive and mostly used on humans rather than for preclinical animal studies. This has led to a gap of knowledge in PET-MR imaging of small animal models used in preclinical research. Our work...
Calcium (Ca) is an essential mineral in the body that helps maintain healthy bone density. Dysreguation of Ca can result in serious health issues and a reliable and efficient method of identifying changes in bone mineral balance can help to provide eaarly diagnosis of deteriorating bone health. The objective of this project is to investigate the application of naturally occurring Ca isotope...
Introduction: A non-invasive imaging method: inhaled hyperpolarized (HP) 129Xe magnetic resonance imaging (MRI) is currently used to measure lung structure and function.1 Simultaneous ventilation/perfusion (V/P) lung measurements of functional gas exchange within the lungs can be obtained using this MRI approach because of the high solubility of xenon in lung tissue as compared to...
Introduction: A great challenge in quantitative dynamic positron emission tomography (PET) imaging is to determine the exact volumes of interest (VOI) with which one wants to work. They have a tremendous impact on the time-activity curves that are used to extract the pharmacokinetic coefficients. Since PET images are functional and not anatomical, using a bijective relationship with a computed...
Magnetic Resonance Imaging (MRI) is a powerful imaging modality with excellent soft tissue contrast. Contrast agent such as iron oxide nanoparticles can be used to “tag” individual cells, distorting the magnetic field around them and allowing the imaging of single cells. Time-lapse MRI can be used to track the motion of tagged cells, providing insights in the studies of inflammatory diseases...
Magnetic resonance imaging (MRI) is widely used as a non-invasive diagnostic technique to visualize the internal structure of biological systems. Quantitative analysis of magnetic resonance signal lifetimes, i.e., relaxation times, can reveal molecular scale information and has significance in the study of brain, spinal cord, articular cartilage, and cancer discrimination. Determination of MR...
Positron Emission Tomography (PET) Imaging of the brain might become the most effective imaging technique to predict Alzheimer's disease. However, the definition of the brain in PET images is low and the lesion area is not easy to define, so the accuracy of traditional machine learning algorithms in predicting Alzheimer's disease from PET images is low. Deep learning algorithms can effectively...
