Conveners
TS-6-2 CAP-COMP Medical Physics (DPMB Symposium) / Physique médicale ACP-OCPM (Symposium DPMB)
- Cornelia Hoehr (TRIUMF)
Introduction: Three-dimensional transrectal ultrasound (3D TRUS) imaging is utilized in prostate cancer diagnosis and treatment, necessitating manual prostate segmentation which is time-consuming and difficult. The purpose of this work was to develop a generalizable and efficient deep learning approach for automatic prostate segmentation in 3D TRUS, trained using a diverse dataset of...
Dosimetry is an important part of radiation therapy, ensuring the prescribed treatment is delivered to the patient and avoiding accidental overexposure of adjacent healthy tissue. This includes characterizing proton beams for proton therapy. However, patients in proton therapy facilities are typically also exposed to secondary neutron fields, that are generated in all materials intercepted by...
Radiotherapy and chemotherapy are the gold standard for treating patients with cancer in the clinic but, despite modern advances, are limited by normal tissue toxicity. The use of nanomaterials, such as gold nanoparticles (GNPs), to improve radiosensitivity and act as drug delivery systems can mitigate toxicity while increasing deposited tumor dose. To expedite a quicker clinical translation,...
Effective local therapy is needed to avoid local progression of the tumor, which may further decrease the development of systemic metastases and increase the possibility for resection. Radiation therapy (RT) is frequently used to locally treat the tumor. One of the major issues in RT for treating cancer is the close proximity of adjacent organs at risk, resulting in treatments doses being...
Diacetylene molecules can self-assemble into crystals, with three-dimensional packing and separation between molecules dictated by the chemical groups on either side of the carbon-carbon triple bonds. When exposed to ionizing radiation, like photon, electron and proton beams used in radiotherapy applications, some diacetylene crystals undergo a radical solid-state polymerization reaction,...
Objective: Dose distribution index (DDI) is a dose-volume parameter used in the treatment planning evaluation. DDI provides the dosimetric estimates on the target coverage, sparings of all organs-at-risk and remaining healthy tissue in the treated organ in a single parameter. In this study, the DDI value was predicted by machine learning model using different algorithms.
Methods: The DDI...
Objective: We built a RT Bot, a chatbot with characterization for the patient, general public and radiation staff to provide educational information regarding radiotherapy using the artificial intelligence. The Bot was personalized by machine learning to detect the user’s temperament and intent in order to provide the best guidance to the user with a human-like response.
Methods: The Bot...
Purpose: A quantitative measure of delivered ionizing radiation is recommended for quality assurance and quality control purposes for patients undergoing radiotherapy treatments. Current dosimeters are not well suited for direct measurements due to atomic composition and size limitations. We are developing a fiber optic probe dosimeter based on radiochromic material for in vivo dosimetry....
