Dr
Rolf Zeisler
(NIST)
20/09/2011, 11:40
Radiopharmaceuticals Chemistry
oral presentation
The 2010 Topical Meeting on Isotopes for Medicine and Industry, the second in a new series of embedded topical meeting of the American Nuclear Society (ANS), was held at the Society’s Winter Meeting, Las Vegas, NV, November 7 – 11, 2010. The meeting series reflects the continuing growth of radioisotopes for both medical and industrial applications and the rapidly expanding research at this...
Dr
Ugur Avcibasi
(1)
20/09/2011, 12:00
Radiopharmaceuticals Chemistry
oral presentation
BLM isolated from the fermentation products of Streptomyces verticillus in 1966 by Umezawa in Japan belongs to a family of structurally related small glycopeptides (1 kDa) that give rise to single-stranded DNA breaks and DNA double-strand breaks (DSBs) in a metal- and oxygen dependent manner1. The BLM used clinically is a mixture of three distinct isomers, A2 (the most abundant, 65 %), B2...
Mrs
Gülcan Ünak
(Ege University, Faculty of Science, Department of Biochemistry)
20/09/2011, 12:15
Radiopharmaceuticals Chemistry
oral presentation
2-Fluoro-2-deoxy-D-glucose radiolabeled with Fluorine-18 (18F-FDG) is routinely used in nuclear medicine as a PET imaging radiopharmaceutical and nucleophilicly synthesised, in general, using mannose triflate as a precursor in the presence of Kryptofix 222TM as a catalyst in acetonitrile as a polar aprotic solvent, which involves the SN2 nucleophilic substitution reaction of 18F to 2-position...
Dr
Stanislav Pavelka
(1Department of Radiometry, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague and 2Central-European Technology Institute, Masaryk University, Brno, Czech Republic)
20/09/2011, 12:30
Radiopharmaceuticals Chemistry
oral presentation
Using [I-125]-labeled iodothyronines as substrates, we applied our newly developed radiometric enzyme assays for iodothyronine deiodinases (IDs) of types 1, 2 and 3 (D1, D2 and D3), as well as the adapted radiometric assays for conjugating enzymes uridine 5’-diphospho-glucuronyltransferase (UDP-GT) and iodothyronine sulfotransferases (ST), in radiopharmacological studies of the interaction of...
