The use of accelerators, in particular of Graphic Processing Units (GPUs), in High Performance Scientific Computing is growing very fast since few years.
GPUs have brought desktop and laptop computers to the Terascale (i.e. bringing computational power beyond a Teraflop), clusters to the Petascale and, in the foreseeable future, supercomputers to the Exascale.
The status of the GPU architecture and an overview about their programmability is evolving will be given.
A review and outlooks of the applications of the GPU technology in the field of High Energy Physics will be discussed as well.