Conveners
Materials and technologies for Health and Environment
- Armandina Maria Lima Lopes (Universidade do Porto (PT))
Materials and technologies for Health and Environment
- Rita Rodrigues (Centre of Physics (CFUM), University of Minho)
Description
Conveners: Mónica Faria, Armandina Lopes, Rita Rodrigues, Marta Almeida, Filipa Mendes
https://videoconf-colibri.zoom.us/j/87872459662?pwd=Sm5ucGlPWWJOckV6N1BNT255THgvUT09
Materials and Technologies for Health and Environment @ CF-UM-UP
The research activities at C2TN´s Health and Environment areas are represented in 2 of the 3 Thematic Strands of the centre. In this seminar we will present the activities performed under the Radiopharmaceutical Sciences and Heath Physics (RSHP) thematic area as well as the research in the Earth Systems, Radioactivity and Cultural Heritage (ESRCH) area.
In the RSHP area the scientific...
Cancer is the second cause of death in Europe and is expected to increase due to the climate changes and population ageing. Early stage detection and effective treatments are keystones to reduce cancer mortality. Nanotechnological systems has been recently demonstrated that are able to perform localized treatment with improved efficiency and reduced side effects. Among the several types of...
This presentation will address the studies on Advanced Materials and Technologies for Health and Environment carried out by researchers at CeFEMA, namely for the efficient production of drinking water, the development of biosensors and medical devices which provide support for vital organs such as kidneys and lungs, the provision of disease diagnosis and targeted therapies, and the mitigation...
Human health and well-being strongly depend on water quality available for consumption. Deterioration of water quality has become one of the most worrying and urgent problems since about 1.6 million people die annually from illness related to unsafe water consumption, being responsible for at least 3900 children deaths per day in developing countries. In this scope, one of the main concerns is...
Ultrashort laser pulses deliver broadband sources for excitation of multiple fluorophores at the same time, therefore providing to medical imaging systems an advance tool for imaging deeper into samples. Furthermore, due to their short pulse duration, and smaller average power they also allow to extend the life time of in vivo samples. Ultrashort laser pulses can also be used in surgery for...
Peptide-based hydrogels provide many advantages for drug delivery, such as low critical gelation concentration, easy tailoring and modulation, and biocompatibility [1]. The self-assembly gelation potentiates novel fabrication strategies and the encapsulation of different composites, such as magnetic nanoparticles and liposomes [2]. The combination with magnetic and/or plasmonic nanoparticles...
Breast cancer is the leading cause of cancer-related deaths in women worldwide [1]. The limitations of the current therapeutic highlight the need for new treatment modalities [2]. In this work, multifunctional lipid nanoparticles were developed for dual chemotherapy-photothermal therapy of breast cancer. Nanoparticles were also functionalized with different targeting agents to improve...
Out-of-field doses are delivery to healthy tissues, which may allow the development of second tumours. Its evaluation with MC methods is essential since these doses are inaccurate when calculated by TPSs. The use of IMRT has been discussed, especially in paediatric patients, as it leads to a "bath" of low doses to large volumes of out-of-field tissue.
This study aims to evaluate out-of-field...
Radionuclide therapy is an anticancer therapeutic modality based on the use of radiopharmaceuticals, which are drugs containing radionuclides emitting ionizing radiation (β- and α particles or Auger-electrons). Many of these radionuclides are also gamma- or positron-emitters and then are suitable for imaging applications using single-photon emission computerized tomography (SPECT) or positron...
During a pandemic when a healthy immune system is more significant than ever, prebiotics gain extra importance. These non-digestible food ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms, protect against cancer and prevent cardiovascular and metabolic issues, are also known to play an important role in the improvement of the immune system [1].
In...
Hemodialysis (HD) is a clinically well-established membrane-based treatment for blood purification under extracorporeal blood circulation. Most of the hemodialyzers/artificial kidneys on the market are composed of synthetic polymer membranes with large pore sizes that allow the removal of uremic toxins (UTs) of large molecular weight. Nevertheless, these membranes are hydrophobic by nature and...
To mitigate the carbon footprint of aerospace industry, light and high-performance materials are currently needed, however they are very difficult to cut and machine. Self-lubricating coatings represent a way to reduce the wear of machining and cutting tools, hence increasing their lifetimes with clear advantages in terms of environmental sustainability. In this sense, it has been recently...
In this work, drug-delivery nanosystems with a combination of chemotherapy and magnetic hyperthermia using doxorubicin-loaded magnetic lipid carriers were investigated. The superparamagnetic iron oxide nanoparticles (SPIONs) and doxorubicin (DOX) were encapsulated in two types of nanostructured lipid carriers (NLC): gelucire-based NLCs (NLC(GEL-DOX-SPIONs)) and palmitate-based NLCs...
