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3rd-INCC

18–23 Sept 2011
Città del Mare, Terrasini - Palermo - Sicily - Italy
Europe/Rome timezone
3rd International Nuclear Chemistry Congress - 3rd-INCC

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Session

Session 7

7
20 Sept 2011, 11:40
Città del Mare, Terrasini - Palermo - Sicily - Italy

Città del Mare, Terrasini - Palermo - Sicily - Italy

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  1. 119. Highlights of the 2010 Topical Meeting on Isotopes for Medicine and Industry
    Dr Rolf Zeisler (NIST)
    20/09/2011, 11:40
    Radiopharmaceuticals Chemistry
    oral presentation
    The 2010 Topical Meeting on Isotopes for Medicine and Industry, the second in a new series of embedded topical meeting of the American Nuclear Society (ANS), was held at the Society’s Winter Meeting, Las Vegas, NV, November 7 – 11, 2010. The meeting series reflects the continuing growth of radioisotopes for both medical and industrial applications and the rapidly expanding research at this...
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  2. 34. In vivo biodistribution of I-131 labeled bleomycin (BLM) and isomers (A2 and B2) on experimental animal models
    Dr Ugur Avcibasi (1)
    20/09/2011, 12:00
    Radiopharmaceuticals Chemistry
    oral presentation
    BLM isolated from the fermentation products of Streptomyces verticillus in 1966 by Umezawa in Japan belongs to a family of structurally related small glycopeptides (1 kDa) that give rise to single-stranded DNA breaks and DNA double-strand breaks (DSBs) in a metal- and oxygen dependent manner1. The BLM used clinically is a mixture of three distinct isomers, A2 (the most abundant, 65 %), B2...
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  3. 142. Attempts to develop new synthesizing methods of 2-fluoro-2-deoxy-d-glucose radiolabelled with fluorine-18 (18F-FDG)
    Mrs Gülcan Ünak (Ege University, Faculty of Science, Department of Biochemistry)
    20/09/2011, 12:15
    Radiopharmaceuticals Chemistry
    oral presentation
    2-Fluoro-2-deoxy-D-glucose radiolabeled with Fluorine-18 (18F-FDG) is routinely used in nuclear medicine as a PET imaging radiopharmaceutical and nucleophilicly synthesised, in general, using mannose triflate as a precursor in the presence of Kryptofix 222TM as a catalyst in acetonitrile as a polar aprotic solvent, which involves the SN2 nucleophilic substitution reaction of 18F to 2-position...
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  4. 7. Radiopharmacological studies: interaction of antidepressant fluoxetine with thyroid hormones metabolism
    Dr Stanislav Pavelka (1Department of Radiometry, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague and 2Central-European Technology Institute, Masaryk University, Brno, Czech Republic)
    20/09/2011, 12:30
    Radiopharmaceuticals Chemistry
    oral presentation
    Using [I-125]-labeled iodothyronines as substrates, we applied our newly developed radiometric enzyme assays for iodothyronine deiodinases (IDs) of types 1, 2 and 3 (D1, D2 and D3), as well as the adapted radiometric assays for conjugating enzymes uridine 5’-diphospho-glucuronyltransferase (UDP-GT) and iodothyronine sulfotransferases (ST), in radiopharmacological studies of the interaction of...
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