Introduction: We have recently demonstrated$^1$ a compressed-sensing (CS)-based undersampling method capable of improving signal-to-noise ratio and image quality of low field images. An optimal choice of pulse sequence would reduce undersampling artefacts and improve image quality; in this work, different sampling patterns in k-space for the X-Centric$^2$ and Sectoral$^{3,4}$ sequences...
In this work we present the first low-field TRASE technique capable of encoding 2D axial slices without switching gradients of the main magnetic field (B0). TRASE is an MR imaging technique that utilizes phase gradients within the radiofrequency (RF) fields to achieve k-space encoding. In doing so, TRASE does not require as many technologies of the main magnetic field, significantly reducing...
Introduction: Ventilation defects in the lungs (1), characterized by impaired airflow and reduced gas exchange, can arise from various factors such as small airway obstructions, mucus accumulation, and tissue damage(2). Hyperpolarized 129Xe/3He lung MRI is an efficient technique used to investigate and assess pulmonary diseases and ventilation defects (3). Current methods for quantifying...
Diffusion magnetic resonance imaging (dMRI) is a method that sensitizes the MR signal to water molecule diffusion, probing tissue on a microstructural level not attainable with traditional MRI techniques. While conventional dMRI has proven useful in many research areas, more advanced techniques are necessary to further characterize tissue microstructure at spatial scales not available with...
Magnetic particle imaging (MPI) is an emerging tracer-based imaging modality that employs the use of magnetic excitation to detect superparamagnetic iron oxide (SPIO) particles. MPI signal is only generated from SPIO and thus there is no signal from tissue. As well, the signal is linearly quantitative with SPIO concentration so the number of SPIO-labeled cells can be calculated from images....
Molecular imaging techniques can be used to track tumour cell proliferation, metastasis, and viability. Tumour cells labelled with superparamagnetic iron oxide (SPIO) and transfected with a luciferase reporter gene can be dually tracked using magnetic particle imaging (MPI) and bioluminescence imaging (BLI). MPI is highly sensitive as signal is generated directly from SPIO. This allows for...
