DNA damage and repair in cells exposed to high and low LET1h 30m
The DNA damage response to different radiation qualities reflects their mode of action. Cells exposed to densely ionising high and scattered low linear energy transfer (LET) radiation react more strongly than to the same dose of each separately. The relationship between DNA double strand break location inside the nucleus and chromatin structure was evaluated using high-resolution transmission electron microscopy in breast cancer cells and will be presented together with fluorescence microscopic data.
dr hab. Katarzyna Grzelak
prof. dr hab. Aleksander Filip Żarnecki