Speaker
Description
The accidents at Chernobyl NPP (April 26, 1986) andFukushima-1 NPP (March 11, 2011) demonstrated have highlighted the pressing challenges in radiation biophysics, including the early diagnostics of radiation injury, assessment of its severity, outcome prediction of radiation sickness, and the development of methods for assessing the effectiveness of therapeutic agents and treatment protocols.
In the present study, an express method has been developed to address these challenges. The method is based on the analysis of diffraction of monochromatic laser radiation on the edges of erythrocytes in a monolayer of whole blood of an irradiated organism. A mathematical model was developed allowing to establish a correlation between the parameters of the erythrocyte distribution function and the characteristics of the intensity distribution in the resulting diffraction pattern observed on the detection screen.
Experimental results demonstrated that the correlation between the studied characteristics exhibits dose- and time-dependent features. It was found that, depending on the radiation dose received and the observation time in the early post-radiation period (one, two and three days after the exposure), the extremum points of the diffraction pattern shift in different way. A criterion was proposed for classifying organisms by the severity of radiation injury at a given dose.
