11–14 May 2026
Valencia Hotel Las Arenas
Europe/Zurich timezone

From image to video in Total-Body PET: Maximum-Likelihood Motion and Activity (MLMA) reconstruction

14 May 2026, 14:40
20m
Valencia Hotel Las Arenas

Valencia Hotel Las Arenas

C/ d'Eugènia Viñes, 22, 24, Poblados Marítimos, 46011 Valencia, Spain

Speaker

Rodrigo José Santo (UMC Utrecht)

Description

The advent of long axial field-of-view (LAFOV) PET has enabled simultaneous imaging of all organs with substantially higher sensitivity. However, motion remains an issue that degrades image quality, as the sensitivity of LAFOV-PET is insufficient to mitigate fast irregular motion at the subsecond timescale. We therefore propose to correct for motion in LAFOV-PET at high frequency (2 Hz) by directly processing list-mode data with the Maximum-Likelihood Motion and Activity (MLMA) reconstruction method, optimized for the large projection space of LAFOV-PET through data reduction. We demonstrate the method on the NEMA body phantom scanned at the IMAS Total-Body PET scanner (I3M Valencia, Oncovision). The results indicate that MLMA can be efficiently applied to LAFOV-PET, realizing the full potential of these high-sensitivity scanners.

Track TBPET
Presentation type Oral

Author

Rodrigo José Santo (UMC Utrecht)

Co-authors

Dr Santiago Jiménez-Serrano (I3M) Prof. Cornelis van den Berg (UMC Utrecht) Prof. Hugo de Jong (UMC Utrecht) Dr Antonio Gonzalez (I3M) Dr Casper Beijst (UMC Utrecht)

Presentation materials

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