Speaker
Description
Total-body positron emission tomography (PET) has attracted increasing attention due to its potential for significantly improved sensitivity and whole-body dynamic imaging compared with conventional PET systems. In this work, we develop a depth-of-interaction (DOI)-enabled total-body PET system with a 200 cm axial field of view (AFOV). The system employs LYSO crystal arrays with a crystal size of 2 × 2 × 20 mm³ coupled to multi-pixel photon counter (MPPC) arrays, and light-sharing windows are used to enable DOI estimation and reduce parallax errors.
The imaging performance of the system was evaluated using several phantoms, including an SZBL logo phantom, a Derenzo phantom, and a one-meter dynamic line source. The reconstructed images demonstrate that structures with dimensions down to 2 mm can be clearly resolved, confirming spatial resolution consistent with the crystal pitch. Dynamic imaging experiments further show clear propagation of 18F-FDG along the line source with high signal-to-noise ratio using 5-s frames, indicating the high sensitivity of the system. In addition, a time resolution of approximately 320 ps was achieved for both single-ring and double-ring configurations.
These results demonstrate that the proposed system provides high spatial resolution, good timing performance, and strong capability for dynamic whole-body imaging. The system shows promise for low-dose imaging and multi-organ dynamic studies in future clinical and research applications.
| Track | TBPET |
|---|---|
| Presentation type | Oral |