11–14 May 2026
Valencia Hotel Las Arenas
Europe/Zurich timezone

Accurate 3D Positioning in Semi-Monolithic PET Detectors including ICS recovery

13 May 2026, 09:20
20m
Valencia Hotel Las Arenas

Valencia Hotel Las Arenas

C/ d'Eugènia Viñes, 22, 24, Poblados Marítimos, 46011 Valencia, Spain

Speaker

Dr Fiammetta Pagano (Instituto de Instrumentación para Imagen Molecular (i3M) – CSIC)

Description

PET image quality depends on accurately determining the lines of response, which requires precise 3D localization of annihilation photon interactions within the detectors. In pixelated crystal arrays, spatial resolution is inherently limited by crystal size and can only be improved by increasing granularity, at significant cost. Monolithic and semi-monolithic arrays overcome this by inferring interaction position from the photosensor light distribution, enabling high spatial accuracy through calibration and software alone.

We present the full 3D position calibration of the Ultra-High-performance Brain (UHB) PET scanner, based on semi-monolithic detectors, using a collimated fan beam and multilayer perceptron (MLP) networks. Overall resolutions of 2.3$\pm$0.6 mm and 2.7$\pm$0.8 mm FWHM were achieved along the monolithic and depth-of-interaction directions, with individual mini-modules reaching ~1.6 mm and ~2.0 mm FWHM, respectively. Slab identification accuracy, applying ICS recovery, reached 78%.

These results demonstrate that semi-monolithic detectors can deliver high 3D spatial resolution across all directions, supporting their application in next-generation brain PET scanners.

Track PSMR
Presentation type Oral

Author

Dr Fiammetta Pagano (Instituto de Instrumentación para Imagen Molecular (i3M) – CSIC)

Co-authors

Dr Francis Loignon-Houle (Instituto de Instrumentación para Imagen Molecular (i3M) – CSIC) Dr David Sánchez (Oncovision SA) Dr Ezzat Elmoujarkach (Department of Radiology, Weill Cornell Medical College, Cornell University) Dr Nicolas Karakatsanis (Department of Radiology, Weill Cornell Medical College, Cornell University) Mr Marc Gil Cervera (Instituto de Instrumentaci´on para Imagen Molecular (i3M)) Mr Luis F. Vidal (Instituto de Instrumentaci´on para Imagen Molecular (i3M)) Julio Barbera (Oncovision (SA)) Jorge Alamo (Oncovision (SA)) Mr Juan Catret (Oncovision (SA)) Dr Sadek Nehmeh (Department of Radiology, Weill Cornell Medical College, Cornell University) Dr Antonio J. Gonzalez Martinez (Instituto de Instrumentación para Imagen Molecular (i3M) – CSIC)

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