Conveners
Session 12: PSMR-Applications
- Casper Beijst
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Christina Valgreen13/05/2026, 16:40
Platinum sponsor talk
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Alejandro López Montes (Inselspital Bern, University of Bern)13/05/2026, 17:00
Background: Alpha-particle radiopharmaceutical therapy (α-RPT) is a promising treatment modality for cancers such as metastatic castration-resistant prostate cancer. Compared to β-emitters (e.g. ¹⁷⁷Lu), α-emitters such as ²²⁵Ac deliver high linear energy transfer over a short range, enabling effective tumour cell killing while sparing surrounding tissue. However, clinical translation is...
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Marianna Inglese (Department of Biomedicine and Prevention - University of Rome Tor Vergata)13/05/2026, 17:20
Accurate non-invasive prediction of isocitrate dehydrogenase (IDH) mutation status remains a major challenge in glioma imaging. Although magnetic resonance imaging (MRI) provides valuable structural and functional information, conventional radiological features lack consistent predictive power across datasets. Recent advances in foundation models trained on large-scale MRI datasets offer a new...
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Marianna Inglese (Department of Biomedicine and Prevention - University of Rome Tor Vergata)13/05/2026, 17:40
Intracranial metastatic disease (IMD) remains a major cause of cancer-related morbidity and mortality, yet the metabolic heterogeneity of brain metastases is poorly characterized in vivo. Conventional imaging typically treats lesions as metabolically homogeneous entities, potentially obscuring biologically meaningful tumor subregions. Here, we present a multimodal imaging framework integrating...
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Robbie Haynes (School of Physics & Astronomy, University of Edinburgh, United Kingdom)13/05/2026, 18:00
Introduction:
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Positron emission tomography (PET) and dynamic contrast-enhanced MRI (DCE-MRI) probe complementary transport processes; $^{18}$F-FDG can undergo carrier-mediated uptake, while gadolinium chelates distribute via passive diffusion. Imaging both modalities in a shared permeability phantom isolates passive transport, allowing the establishment of a baseline permeability ratio...