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We present results for $f_K/f_{π}$ with $N_f=2+1$ flavors, along with a determination of $|V_{us}|$ and a study on the unitarity of the first row of the Cabibbo-Kobayashi-Maskawa (CKM) matrix after introducing strong isospin-breaking and QED effects. The results obtained are based on a combination of a Wilson unitary action and a mixed action setup using Wilson twisted mass fermions in the valence, based on CLS ensembles. The combination of the two regularizations enables a more precise control over the continuum limit extrapolation, as both setups must share the same continuum limit, yet can exhibit distinct cutoff effects.