Mixing in the D0 system may provide a sensitive probe for new physics beyond the Standard Model (SM). The SM predictions are small (<10-3) for the mixing parameters x, y which, in the absence of CP-violation, measure the mass (x = DM/G) and lifetime (y = DG/2G) difference of the CP-eigenstates in the D0 system. New physics may significantly enhance x while y is expected to be dominated by SM processes.
The BaBar detector at the e+e- storage ring PEP-II provides the opportunity of studying charm decays with unprecedented statistics and purities. Two experimental methods will be described in detail: The determination of y from the D0 lifetime difference in the decays K-p+ and K-K+ , and the extraction of y, x2 and the wrong-sign (D0 -> K+p-) decay rate from the time evolution of the D0 decay rate. Preliminary BaBar results for y and the wrong-sign decay rate will be presented.