Boron Neutron Capture Therapy (BNCT) - Status and recent developments

by Dr. Raymond Moss, Giuseppe Daquino (RC of European Commission, Petten, NL, and CERN/PH)

Monday 25 Apr 2005, 16:30 → 17:30 Europe/Zurich

500/1-001 - Main Auditorium (CERN)

BNCT is a promising therapy for the treatment of inoperable cancers. It is a bimodal form of radiotherapy based on thermal neutron capture in B-10, producing a highly specific treatment, due to the emission of Li-7 and alpha particles, both characterized by high LET. Clinical trials are in progress in Europe, USA, Japan and Argentina. At the High Flux Reactor in Petten (NL), clinical trials on the treatment of brain tumours have been in progress since 1997. Due to its complex (radiation) dose distribution, treatment planning (TP) becomes a critical issue. Recently, PET imaging of the B-10 localization demonstrated its heterogeneous macro-distribution. To this purpose, an ad-hoc TP system has been developed in order to combine the CT anatomic data and the PET functional data on the boron distribution. The status of the clinical research and recent developments will be presented.



Organiser(s): Rolf Landua / PH-EP Department

Note: * Please note unusual day!

**Tea and coffee will be served at 16:00

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