In this talk, I will discuss the general question of implementing a chiral MSSM like D-brane sector in Type IIB orientifold models together with complete moduli stabilisation via F-terms induced by fluxes and space-time instantons. It turns out that in principle this is not possible and D-terms have to be taken into account. I will then illustrate this observation in the framework of the Large Volume Scenarios and I comment on further model building rules.