Speaker
Dr
John Hoppin
(Research Center Juelich)
Description
In recent years we have presented our multiplexing multi-pinhole SPECT imaging
technique (HiSPECT) and its extensive applications in mouse and rat imaging. The
basis of our imaging approach is the upgrading of clinical gamma cameras with
pyramid collimators outfitted with interchangeable multi-pinhole apertures. To date
we have designed more than thirty different apertures, almost all of which have
been focused on rodent imaging. In this work we present an extension of our
technique to larger fields of view (FOV). Specifically, we present results of cat
brain, dog prostate and human hand and foot imaging on three different gamma
cameras upgraded with the HiSPECT module. The cat brain imaging was performed on a
Trionix Triad at a radius of rotation (ROR) of 60mm with reconstructed resolutions
of 2.1mm with a sensitivity of 650cps/MBq in a cylindrical FOV with diameter 70mm
and length 70mm. Oncological dog studies were performed on a Picker Prism 3000 at
an ROR of 130mm with reconstructed resolutions of 3.5mm and a sensitivity of
270cps/MBq in a cylindrical FOV of 100x100mm. Hands and feet of arthritis patients
were imaged with a Picker Prism 2000 at RORs of 90 and 130mm respectively.
Reconstructed resolutions of 3.1mm were achieved at sensitivities of 150cps/MBq for
a cylindrical FOV of 120x180mm. Detailed descriptions and results from all three
large FOV applications.
Author
Dr
John Hoppin
(Research Center Juelich)
Co-authors
Dr
Christian Lackas
(Research Center Juelich)
Dr
Nils Schramm
(Research Center Juelich)