9–12 May 2006
Palais du Pharo, Marseille
Europe/Zurich timezone

Phase contrast enhanced high resolution X–ray imaging and tomography of soft tissue

10 May 2006, 17:15
15m
Palais du Pharo, Marseille

Palais du Pharo, Marseille

oral S3_S4 others modalities Other Modalities

Speaker

Mr Carlos Granja (researcher)

Description

Imaging of soft tissue demands high sensitivity and contrast enhancing techniques in order to reliably detect and resolve structures and patterns of small size and of similar atomic composition. For these purposes, traditional X–ray transmission–based radiography is limited by the low and homogenous absorption of X–rays in soft tissue. Phase shift contrast imaging can bring additional information by diffraction and interference effects in the wave–nature properties of photon beams induced by varied media and structures in soft tissue. We investigate the potential and advantages of phase contrast as a supplementary tool in X-ray imaging and tomography of soft tissue in small insects and organic samples. We implement high spatial resolution soft X–ray 2D and 3D imaging making use of the state–of–the–art Medipix–2 semiconductor pixel detector and microspot X–ray tube in addition to geometric magnification. We achieve high performance soft X–ray detection by our single photon counting system having high sensitivity and unlimited dynamic range. Data collection has been eased by a new USB–based readout together with online image generation. Improved signal reconstruction techniques make use of advanced statistical data analysis, enhanced beam hardening correction using individual pixel calibration and devoted algorithms for tomographic reconstruction.

Authors

Mr Carlos Granja (researcher) Mr Jan Jakubek (researcher)

Co-authors

Mr Jiri Dammer (student) Mr Josef Uher (researcher) Mr Richard Tykva (researcher) Mr Robert Hanus (researcher) Dr Stanislav Pospisil (researcher, director) Mr Tomas Holy (student) Mr Vykydal Vykydal (researcher)

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