9–12 May 2006
Palais du Pharo, Marseille
Europe/Zurich timezone

Molecular Breast Imaging: first results from Italian National Health Institute clinical trials

11 May 2006, 09:00
15m
Palais du Pharo, Marseille

Palais du Pharo, Marseille

oral S5-S6 medecine Clinical Imaging

Speaker

Dr Francesco Cusanno (Istituto Nazionale Fisica Nucleare)

Description

Dedicated high resolution detectors are needed for detection of small tumors by molecular imaging with radionuclides. Absorptive collimation typically used for imaging single photon emitters, results in a strong reduction in efficiency. System based on electronic collimation is offering higher efficiency but is complex and expensive. For these reasons, the simulations and measurements have been performed to design dedicated high resolution mini gamma cameras. Critical parameters are contrast and Signal to Noise Ratio (SNR). Intrinsic performance (spatial resolution and pixel identification, linearity) were optimized as first. Pixellated scintillator arrays (NaI(Tl)) of different pixel sizes were coupled to arrays of PSPMT’s with different anode dimensions (6 x 6 mm2 and 3 x 3 mm2). Detectors having a Field Of View (FOV) of 100 x 100 mm2 and 150 x 200 mm2 were designed and built. The electronic system allows readout of all anode pad signals. The collimation technique was then considered and the limits of the coded aperture option were studied. First clinical trials performed in the framework of the Italian National Insitute project and Universities of Rome Tor Vergata and Napoli will be presented.

Author

Dr Evaristo Cisbani (Istituto Superiore di Sanita')

Co-authors

Mr Evaristo Colilli (Istituto Superiore di Sanita') Mr Fabio Santavenere (Istituto Superiore di Sanita') Mr Fausto Giuliani (Istituto Superiore di Sanita') Dr Francesco Cusanno (Istituto Nazionale Fisica Nucleare) Dr Franco Garibaldi (Istituto Superiore di Sanita' and Istituto Nazionale Fisica Nucleare) Dr Maria Lucia Magliozzi (University "La Sapienza") Mr Massimo Gricia (Istituto Superiore di Sanita') Mr Maurizio Lucentini (Istituto Superiore di Sanita') Mr Piero Veneroni (Istituto Nazionale Fisica Nucleare) Mr Rolando Fratoni (Istituto Superiore di Sanita') Dr Sergio Torrioli (C.I.S.B.) Dr Stan Majewski (Jefferson Lab)

Presentation materials

There are no materials yet.