Speaker
Mr
Panagiotis Gonias
(Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)
Description
The recently developed GATE, a Geant4 Application for Tomographic Emission, is a
Monte Carlo simulation platform developed for PET and SPECT and is freely distributed
by the OpenGATE collaboration. GATE is based on a powerful simulation core, Geant4
toolkit, that includes well-validated physics models, geometry modeling tools and
efficient visualization utilities, and, uses newly developed software components for
data analysis and image reconstruction. GATE provides the ability of modeling
time-dependent phenomena, such as geometry element movements and source decay
kinetics, allowing the simulation of time curves under realistic acquisition
conditions. The purpose of this paper was to validate a GATE model for the simulation
of the Siemens PET/CT biograph™ 6 scanner. This three-dimensional GATE model
simulated 24336 LSO ( Lutecium Oxyorthosilicate) detectors grouped into 144 blocks as
the vendor’s specifications. The GATE results were compared to experimental data
obtained in accordance to the NEMA NU 2-1994 and NEMA NU 2-2001 protocols. The
Phantoms used by these protocols were also modeled within GATE, allowing us to
simulate the sensitivity, scatter fraction, count rate performance and spatial
resolution. The simulated sensitivity was within 1% compared to the experimental one,
the simulated scatter fraction agreed within 2.5% of the measured value. The
experimental peak true count rate and the peak activity concentration were matched by
the simulated results to within 0.5% and 0.2% respectively. The spatial resolution of
the simulated scanner matched the experimental results to within 0.4 mm.
Authors
Mr
Nikolaos Bertsekas
(Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)
Mr
Panagiotis Gonias
(Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)
Co-authors
Mr
Anastasios Gaitanis
(Department of Medical Instruments Technology, Technological Educational Institution of Athens, Ag. Spyridonos, Aigaleo, 122 10 Athens, Greece)
Mr
Antonis Daskalakis
(Department of Medical Physics, Medical School, University of Patras, 265 00 Patras, Greece)
Dr
Dimitrios Nikolopoulos
(Department of Medical Instrumentation, Technological Educational Institution of Athens, 12210 Egaleo, Greece)
Prof.
Dionysis Cavouras
(Department of Medical Instruments Technology, Technological Educational Institution of Athens, Ag. Spyridonos, Aigaleo, 122 10 Athens, Greece)
Dr
George Loudos
(Department of Electrical and Computer Engineering, National Technical University of Greece)
Prof.
George Panayiotakis
(Department of Medical Physics, School of Medicine, university of Patras,Patra,Greece)
Mr
George Saatsakis
(Biomedical Engineering Department, University Hospital “Aretaieion”, University of Athens, Vasilisis Sofias 76, Athens)
Prof.
Ioannis Kandarakis
(Department of Medical Instrumentation, Technological Educational Institution of Athens, 12210 Egaleo, Greece)
Mr
Laertis Papaspyrou
(Department of Medical Instruments Technology, Technological Educational Institution of Athens, Ag. Spyridonos, Aigaleo, 122 10 Athens, Greece)
Mr
Nikolaos Karakatsanis
(Department of Electrical and Computer Engineering, National Technical University of Athens, 9 Iroon Polytechniou, 15780 Zografos, Greece)
Mr
Nikolaos Sakelios
(Department of Electrical and Computer Engineering, National Technical University of Athens, 9 Iroon Polytechniou, 15780 Zografos, Greece)
Mr
Panagiotis Liaparinos
(Department of Medical Physics, Medical School, University of Patras, 265 00 Patras, Greece)