Speakers
Prof.
Franck Debardieux
(Institut de Biologie du Developpement de Marseille, France)Dr
Pierre Delpierre
(Centre de Pysique des Particules de Marseille)
Description
The PIXSCAN is a small animal CT-scanner based on hybrid pixel detectors. These
detectors provide very large dynamic range of photons counting at very low detector
noise. They also provide high counting rates with fast image readout. Detection
efficiency can be optimized by selecting the sensor medium according to the working
energy range. Indeed, the use of CdTe allows a detection efficiency of 100% up to 50
keV. Altogether these characteristics are expected to improve the contrast of the
CT-scanner, especially for soft tissues, and to reduce both the scan duration and the
absorbed dose. A proof of principle has been performed by assembling into a PIXSCAN
prototype the photon counting pixel detector initially built for detection of X-ray
synchrotron radiations. Despite the relatively large pixel size of this detector (330
x 330 µm2), we can present nice tomographic reconstruction of mice at good contrast
and spatial resolution. A new photon counting chip (XPAD3) is designed in
sub-micronique technology to achieve 130 x 130 µm2 pixels (see the poster "XPAD3: A
new photon counting chip for X-ray CT-Scanner " at this conference). This improved
circuit has been equipped with an energy selection circuit to act as a band-pass
emission filter. Such energy selection should improve the image quality by cutting
the low and high energy queues after the pre-filtered X-ray source. For example in
the presence of iodinated contrast agents, one can select an energy window lower and
higher than the iodine photoelectric absorption jump and, by image subtraction, have
the iodine only. Furthermore, the PIXSCAN XPAD3 hybrid pixel detectors will be
combined with the Lausanne ClearPET scanner demonstrator (see poster "Measured and
Simulated Specifications of the Lausanne ClearPET Scanner Demonstrator" at this
conference). CT image reconstruction in this non-conventional geometry is under
study for this purpose.
Authors
Prof.
Franck Debardieux
(Institut de Biologie du Developpement de Marseille, France)
Dr
Pierre Delpierre
(Centre de Pysique des Particules de Marseille)
Co-authors
Alain bonissent
(Centre de Pysique des Particules de Marseille)
Benoit Chantepie
(Centre de Pysique des Particules de Marseille)
Bernard Caillot
(CNRS Grenoble & D2am CRG beam line, France)
Bernard Dinkespiler
(Centre de Pysique des Particules de Marseille)
Prof.
Christian Morel
(Centre de Pysique des Particules de Marseille)
Christian Mouget
(CNRS Grenoble & D2am CRG beam line, France)
Christophe Meessen
(Centre de Pysique des Particules de Marseille)
Dominique Sappey-Marinier
(CREATIS, UMR-CNRS-5515, INSERM-U630, Lyon, France)
Eric Vigeolas
(Centre de Pysique des Particules de Marseille)
Françoise Peyrin
(CREATIS, UMR-CNRS-5515, INSERM-U630, Lyon, France)
Geneviève Rougon
(Institut de Biologie du Développement de Marseille Luminy (IBDML), France)
Ivan Koudobine
(Centre de Pysique des Particules de Marseille)
Jean-Claude Clemens
(Centre de Pysique des Particules de Marseille)
Jean-François berar
(CNRS Grenoble & D2am CRG beam line, France)
Nathalie Boudet
(CNRS Grenoble & D2am CRG beam line, France)
Patrick Breugnon
(Centre de Pysique des Particules de Marseille)
Patrick Pangaud
(Centre de Pysique des Particules de Marseille)
Rana Kouri
(Centre de Pysique des Particules de Marseille)
Solène Valton
(CREATIS, UMR-CNRS-5515, INSERM-U630, Lyon, France)
Stephanie Basolo
(Centre de Physique des Particules de Marseille(CPPM-IN2P3), France)
Valery Matarazzo
(Institut de Biologie du Développement de Marseille Luminy (IBDML), France)