Speaker
Dr
Keishi Kitamura
(Shimadzu Corporation)
Description
The jPET-D4 is a brain PET scanner composed of 4-layer depth-of-interaction (DOI)
detectors with a large number of GSO crystals, which achieves both high spatial
resolution and high scanner sensitivity. Since the sensitivity of each crystal
elements highly depends on the depth of DOI layers and the energy of an incident
gamma ray, it is difficult to estimate normalization factors and scatter components
with high statistical accuracy. In this work, we implemented a hybrid scatter
correction method combined with component-based normalization, which estimates
scatter components with a dual energy acquisition through an estimation of trues
from an upper energy window using a convolution subtraction method. In order to
reduce statistical noise in sinograms, the implemented scheme uses the DOI
compression (DOIC) method, which combines deep pairs of DOI layers into the nearest
shallow pairs of DOI layers with natural detector samplings. Since the compressed
data preserve block detector configuration as if acquired with ‘virtual’ detectors
having a high stopping power for the gamma rays, the correction methods can be
applied directly to DOIC sinograms. To investigate the performance, we compare the
DOIC based correction with the conventional non-DOI correction using phantom
measurements of the jPET-D4. The results indicate that the quality of normalization
and scatter correction of the DOIC data is almost the same as those of the non-DOI
data, while the statistical error in uncompressed DOI data increases rapidly with
the depth of DOI layers. The proposed method also allows us to improve
computational efficiency and to reduce acquisition time and storage size for
normalization data even for multi-layer DOI detectors.
Author
Dr
Keishi Kitamura
(Shimadzu Corporation)
Co-authors
Mr
Akihiro Ishikawa
(Shimadzu Corporation)
Dr
Eiji Yoshida
(National Institute of Radiological Sciences)
Dr
Hideo Murayama
(National Institute of Radiological Sciences)
Dr
Taiga Yamaya
(National Institute of Radiological Sciences)