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Prof. Roger LECOMTE (Université de Sherbrooke)10/05/2006, 08:30S1-S2oralThe growing field of molecular imaging has accelerated the introduction of novel technologies and the development of new methodologies to investigate biologic processes in living animals that can be used as models of human diseases. Because of their unrivalled sensitivity, radiotracer-based imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron...Go to contribution page
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Dr Craig Woody (Brookhaven National Lab)10/05/2006, 09:00S1-S2oralThe RatCAP is a small, head mounted PET tomograph that has been designed to image the brain of a conscious rat. It will allow PET imaging studies to be carried out on laboratory rats without the use of anesthesia, which severely suppresses many of the brain functions and neurological activities that one would like to study using PET, and also prevents studying animal behavior while...Go to contribution page
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Dr Nicola Belcari (Department of Physics, University of Pisa)10/05/2006, 09:15S1-S2oralObjectives: The YAP-(S)PET is the only small animal scanner that combines the PET and SPECT techniques on a single gantry. It is made up of four detector heads: each one is composed of a 4 cm × 4 cm YAP:Ce matrix of 20 × 20 elements, 2 mm × 2 mm × 25 mm each, coupled to a PS-PMT. Due to the relatively large solid angle subtended by each crystal matrix the system is subject to an...Go to contribution page
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Dr Karl Ziemons (Forschungszentrum Juelich)10/05/2006, 09:30S1-S2oralThe ClearPET(tm) Neuro scanner, a dedicated high performance small animal PET scanner at Forschungszentrum Jülich GmbH, has been developed as a device for molecular neuroimaging in rodents and non-human primates under physiological conditions. Innovative features developed within the Crystal Clear Collaboration (CCC) have been implemented in particular with regard to crystal material and...Go to contribution page
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Dr Giovanni Di Domenico (Universita' di Ferrara & INFN-Sezione di Ferrara - Italy)10/05/2006, 09:45S1-S2oralPositron Emission Tomography (PET) of small animals is a good and promising in-vivo and non-invasive technique which has helped the recent emergence of molecular imaging. The fast development of this research fields needs new technological devices to reach better and better performances in term of spatial resolution and sensitivity. To satisfy these growing requests, small animal PET...Go to contribution page
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Dr José Benlloch (IFIC, Valencia)10/05/2006, 10:00S1-S2oralWe have constructed a small animal PET with four identical detector modules, each consisting of a continuous LSO crystal attached to a Flat Panel PSPMT. The dimensions of the continuous crystal are 50 × 50 mm2 and 10 mm thickness. The modules are separated 11 cm between each other in the scanner. In this paper we discuss the method used for the calibration of the camera for this...Go to contribution page
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Dr David Guez (IPHC)10/05/2006, 10:15S1-S2oralA new Multi Modality Imaging System for Small Animal (AMISSA) is under development, at the Hubert-Curien Multidisciplinary Institute (IPHC, France). Within this framework, a new PET design is under study[1]. This system is aimed to achieve a spatial resolution of 1 µl in the entire field of view (FOV), along with a high detection efficiency, close to the geometrical efficiency in the...Go to contribution page
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Dr Oleg Blagosklonov (University of Franche-Comte and Jean Minjoz University Hospital, Besançon, France)10/05/2006, 11:00S1-S2oralIsotope studies provide valuable data about an organ’s function in vivo. Thanks to positron emission tomography (PET) using the radiolabeled natural metabolites, such as [18F]-2-fluoro-deoxy-d-glucose (FDG), biological and physiological meaning of nuclear medicine scans has been considerably increased. Moreover, the higher spatial resolution of PET scans allows the direct assessment of...Go to contribution page
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Dr Sébastien jan (CEA/DSV/DRM/SHFJ - Orsay France)10/05/2006, 11:15S1-S2oralPositron Emission Tomography is an essential modality for small animal molecular imaging. Growing requirements in high animal throughput and precision imply the optimization of acquisition parameters and protocols. Monte Carlo simulations are essential tools for assisting these developments, improving image quantification and data analysis. In this work we use the GATE platform [1]...Go to contribution page
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Dr LOICK VERGER (CEA-LETI)10/05/2006, 11:30S1-S2oralIncreasing interest in room temperature solid state detectors like CdTe/CdZnTe for gamma-ray imaging has marked the last ten years with progress in crystal growth, device technology, integrated electronics and signal processing. The purpose of this paper is to present recent technological advances and potential applications in gamma-ray imaging. A new method to grow very large...Go to contribution page
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Dr Maria Cristina Montesi (Dipartimento di Scienze Fisiche, Università di Napoli Federico II and INFN sez. Napoli, Napoli, Italy)10/05/2006, 11:45S1-S2oralWe describe MediSPECT a newly developed system for SPECT studies on small animals with a small field of view (FOV) and high spatial resolution. The detection imaging system is based on a CdTe pixel detector (a 256x256 matrix of 55 micrometers square pixels) operating in single photon counting for direct detection of X-rays and gamma- rays with low and medium energy (e.g. I-125, 27-35...Go to contribution page
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Dr Christian Lackas (Research Center Juelich)10/05/2006, 12:00S1-S2oralMulti-Pinhole SPECT has become a proven modality in small-animal molecular imaging. Although the spatial-resolution capabilities of SPECT are greater than those of PET, the latter is generally considered the gold-standard nuclear imaging modality due to high-sensitivities. In this work, we present a high-throughput SPECT system that achieves submillimeter reconstructed resolutions...Go to contribution page
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Dr George Loudos (Biomedical Simulation and Imaging Application Laboratory, School of Electrical and Computer Engineering, National Technical University of Athens)10/05/2006, 12:15S1-S2oralA mouse sized camera has been built in terms of a collaboration between the presenting insitutions. The system will be used for the performance of dynamic studies in small animals, in order to evaluate novel radiopharmaceuticals. The active area of the detector is approximately 48 mm x 96 mm allowing depiction of the entire mouse in a single view. The system is based on two flat-panel...Go to contribution page
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