I’m chief of the Molecular Imaging and Therapy Service, Department of Radiology at Memorial Sloan Kettering Cancer Center. I authored more than 150 peer reviewed, original publications and review articles, and supervised more than 50 undergraduate students, graduate students, postdoctoral researcher, medical residents and fellows.
My current research is focused on the development and clinical evaluation of novel radiopharmaceuticals for the diagnosis and therapy of cancer. Ongoing projects include clinical and preclinical somatostatin and gastrin releasing peptide receptor antagonists for the diagnosis of therapy of neuroendocrine tumors and prostate cancer. These compounds have shown favorable characteristics in animal studies and very encouraging results in early clinical studies.
A further area of research is the use of PET/CT and PET/MR for radiation treatment planning and monitoring tumor response to therapy. In this area we are working on technical improvements of PET imaging (e.g. gated and high resolution PET imaging) as well as on clinical trials assessing the impact of PET imaging on patient outcome. Ongoing projects include radiation treatment planning of lung cancer head and neck cancer and gliomas.
