Production of Medical Radionuclides in Russia and Isotope Program in the Institute for Nuclear Research, Moscow-Troitsk

by Boris Zhuikov (Institute for Nuclear Research of Russian Academy of Sciences)

Thursday 21 Jun 2018, 14:15 → 15:30 Europe/Zurich

30/7-018 - Kjell Johnsen Auditorium (CERN)

Reactor and accelerator centers in Russia produce various medical isotopes mainly for export needs. These facilities belong to different governmental agencies and ministries: ROSATOM, Russian Academy of Sciences (now operated by FASO), Kurchatov National Research Center, Ministry of Education and Science, Ministry of Healthcare, Ministry of Defense, and also a few private companies. The existing linear accelerator at the Institute for Nuclear Research (Moscow-Troitsk) and several prospective installations are able to provide mass production of radionuclides that can substitute, to a certain extent, for the traditional medical isotopes.

INR has developed several new technologies for producing 82Sr, 82Sr/82Rb-generator, 225Ac, 117mSn, 68Ge, 72Se etc. at intensive beam (up to 140 µA) of middle-energy protons (up to 160 MeV). Fruitful collaboration of INR with LANL (Los Alamos, USA), BNL (Brookhaven, USA), TRIUMF (Vancouver, Canada), ARRONAX (Nantes, France) and ZEVACOR (Indianapolis, USA) played a key role in these developments. Hundreds of thousands of patients have passed diagnostics in USA and some in Russia with isotopes produced in Troitsk, and millions with the technologies developed with INR participation and used in different facilities.

In particular, INR has installed a new radiochemical technology for 82Sr production from irradiated Rb targets followed Sr extraction by direct sorption from liquid metal. INR has developed 82Sr/82Rb-generator more efficient than American analog, and this generator has passed clinical trials for diagnostics of cardiology and neurooncology diseases with PET.

A method for producing in multi-Curie amounts therapeutical α-emitting 225Ac, 223Ra and 233Pa from Th-target at proton energies 160 MeV has been also developed. 225Ac obtained in this way is prospective for preparation of a 225Ac/213Bi isotope generator.

There are problems in the deployment of medical isotope production in Russia. New technology developments can be efficient through international collaboration.

ATS Seminars Organisers: H. Burkhardt (BE), M. Modena (ATS), T. Stora (EN)

Coffee / tea will be served after the seminar in room 30/7-012 next to the Auditorium

2018 Geneva-Zhuikov-7sh.pdf