ISOLDE Workshop and Users meeting 2022

Session

Biophysics

Dec 2, 2022, 9:00 AM

503/1-001 - Council Chamber (CERN)

Conveners

Biophysics

• Ulli Koester (Institut Laue-Langevin (FR))

50. From magnetic moments and biochemistry to future β-NMR studies at VITO

Marcus Jankowski (Technische Universitaet Darmstadt (DE))

12/2/22, 9:00 AM

Invited (In person)

While NMR is an indispensable technique in physics, chemistry, and biology, it bears constraints of low sensitivity, which make it challenging or unsuitable to study a variety of common elements. These limitations are widely overcome by β-particle-detecting NMR. It benefits from combining a hyperpolarisation of the nuclear spin generated through optical pumping, and an efficient detection of...

62. The recent campaign of collection and chemical separation of 149Tb, along with its subsequent application for preclinical therapy studies

Nicholas Philip Van Der Meulen (Paul Scherrer Institute (CH))

12/2/22, 9:30 AM

Submitted oral (In person)

Terbium is a unique element in that it includes a quadruplet of radioisotopes suitable for diagnostics and therapy in nuclear medicine [1]. With their characteristics, it can contribute to the theragnostics concept, where one can treat what one images. Much success has been gained from the PSI-ISOLDE collaboration, with the collection and purification of 149Tb (α-emitter, T1/2 = 4.1 h – for...

36. Intense and pure samples of 129m,131m,133mXe for a novel medical imaging technique, gamma-MRI

Mateusz Jerzy Chojnacki (Universite de Geneve (CH))

12/2/22, 9:45 AM

Submitted oral (In person)

Gamma-MRI is a future imaging modality that should allow the simultaneous exploitation of the sensitivity of gamma-ray detection (SPECT) and the spatial resolution and flexibility of MRI. The approach uses, like in SPECT, gamma-emitting nuclei, which are highly polarized and thus exhibit anisotropic gamma-ray emission, whereas their spins are rotated by rf pulses, like in MRI. The signal in...