22–23 May 2023
DESY, Hamburg, Germany
Europe/Zurich timezone

The 100μPET project: Simulation of the next generation PET scanner with monolithic silicon pixel sensors

22 May 2023, 13:35
25m
Seminar room 4 (DESY, Hamburg, Germany)

Seminar room 4

DESY, Hamburg, Germany

Building 1B, 2nd floor
Applications & Studies Applications and studies

Speaker

Jihad Saidi (Universite de Geneve (CH))

Description

The 100µPET project, led by the University of Geneva, the University of Luzern, and the École Polytechnique Fédérale de Lausanne, aims at the development of a small-animal positron emission tomography (PET) scanner with ultra-high-resolution molecular imaging capabilities.

This is achieved with compact and modular stacks of multiple thin monolithic pixel detectors bonded to flexible printed circuits (FPC) via flip-chip, thus resulting in unprecedented scanner depth-of-interaction and volumetric granularity.

Simulations performed with the Allpix$^2$ framework allowed the optimisation of the scanner sensitivity by analysing effects of different design choices such as, for example, the specifications of the Si layers and the impact of adding high-Z photon conversion layers, the thickness of the FPCs or cooling blocks. Simulations were also done to generate realistic scanner data for imaging reconstruction. Very large datasets with billions of events were produced with different source phantoms. A point-spread-function of 0.2 mm was found, free of parallax effect, resulting in a volumetric spatial resolution of ~ 0.015 mm$^3$ - one order of magnitude better than modern scanners.

The work developed within the Allpix$^2$ framework, including the PetAnalysis module and improvements for faster data generation, will be presented in this contribution.

Author

Jihad Saidi (Universite de Geneve (CH))

Co-authors

Andrea Pizarro Medina Antonio Picardi (Universite de Geneve (CH)) Carlo Alberto Fenoglio Didier Ferrere (Universite de Geneve (CH)) Frank Raphael Cadoux (Universite de Geneve (CH)) Fulvio Martinelli (Universite de Geneve (CH)) Giuseppe Iacobucci (Universite de Geneve (CH)) Jorge Andres Sabater Iglesias (Universite de Geneve (CH)) Lorenzo Paolozzi (CERN) Luca Iodice (Universita degli Studi di Napoli Federico II (IT)) Mateus Vicente Barreto Pinto (Universite de Geneve (CH)) Mr Roberto Cardella (Universite de Geneve (CH)) Sergio Gonzalez Sevilla (Universite de Geneve (CH)) Stefano Zambito (University of Geneva) Thanushan Kugathasan (CERN)

Presentation materials