26–31 May 2024
Western University
America/Toronto timezone
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Designing protein-based artificial molecular motors

28 May 2024, 15:15
30m
SSC Rm 2024 (cap. 137) (Social Science Centre, Western U.)

SSC Rm 2024 (cap. 137)

Social Science Centre, Western U.

Invited Speaker / Conférencier(ère) invité(e) Physics in Medicine and Biology / Physique en médecine et en biologie (DPMB-DPMB) (DPMB) T2-3 Active Matter | Matières actives (DPMB)

Speaker

Nancy Forde (Department of Physics, Simon Fraser University)

Description

Molecular motors are nanoscale machines capable of transducing chemical energy into mechanical work. Inspired by biology, our transnational team has conceived different designs of artificial motors comprised of protein building blocks – proteins, because these are Nature's choice of such functional units. We have recently characterized the motility of one of these designs – the Lawnmower – and found that its dynamics demonstrate motor-like properties. I’ll describe the burnt-bridge ratchet principle of Lawnmower motility and our simulations and experiments that explore its motion.

Work in my group on this project led by PhD graduate Chapin Korosec, with funding from NSERC.
Publication: Korosec et al., Nature Communications 15, 1511 (2024)

Keyword-1 Molecular motors design
Keyword-2 Active matter
Keyword-3 Instrumentation

Primary author

Nancy Forde (Department of Physics, Simon Fraser University)

Presentation materials

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