12–14 Mar 2025
Facultad de Ciencias Físicas UCM
Europe/Madrid timezone

MLTiming: Pairwise Learning for Improving Timing Resolution in TOF-PET

13 Mar 2025, 12:00
30m
M2/Sala de Grados (Facultad de Ciencias Físicas UCM)

M2/Sala de Grados

Facultad de Ciencias Físicas UCM

Plaza de las Ciencias 1, Ciudad Universitaria, 28040 Madrid, Spain
Oral presentation Fast scintillators for time-of-flight PET and other imaging modalities Day 2

Speaker

José Andrés Avellaneda González

Description

Accurate timing characterization of detected radiation events in Positron Emission Tomography (PET) provides Time-of-flight (TOF) information for detected coincidences, which improves the signal-to-noise ratio of the reconstructed images. In this work, we propose a method to train machine learning (ML) models to assign accurate timestamps to events measured in radiation detectors making use of just the signals detected by individual detectors, without the need of resorting to other detector signals. We performed a proof-of-concept study using four different neural network (NN) architectures, trained with event pairs constructed with the measured signal and a delayed version of it. The delay is used as a label in the training process. The proposed trained model was evaluated with data acquired with a $^{22}$Na point source using a pair of LaBr$_3$(Ce) crystals in the shape of truncated cones coupled to fast photomultiplier tubes (PMTs). The detected $\gamma$-ray pulses were sampled at 5 Gsamples/s. A decrease of 15$\%$ in Mean Absolute Error (MAE) and of 16$\%$ in Coincidence Time Resolution (CTR) compared to the analog constant fraction discrimination (A-CFD) -from 284 $\pm$ 3 ps to 238 $\pm$ 1 ps- method was achieved. The proposed ML methods requiere moderate computing power and are fast enough (>250kcps) for its practical implementation in PET scanners with many detectores modules.

Author

Co-authors

JOAQUIN LOPEZ HERRAIZ (Complutense University of Madrid) Jose Manuel Udias Moinelo Prof. Luis M Fraile (Universidad Complutense (ES)) Dr Victor Sánchez-Tembleque (Universidad Complutense de Madrid)

Presentation materials