Speaker
Ulli Koester
(Institut Max von Laue-Paul Langevin (FR))
Description
We report on first results with ISOLDE radioisotopes collected in the frame of the LOI-121.
We were able to demonstrate in vivo PET and SPECT imaging using 152Tb and 155Tb for the first time. Also in-vivo PET imaging with the long-lived in vivo generator 140Nd/140Pr was demonstrated, thus enabling longitudinal in vitro and in vivo PET monitoring of the biodistribution of antibodies over many days.
Various carrier-free Auger electron emitters are used for basic radiobiological research on the microdosimetry of such short-range radiation.
Yields and beam contaminants were determined for a variety of radioisotopes that are of interest for medical applications.
An outlook will be given on the planned research program and possible midterm upgrades (HIe-Isolde).
Primary author
Ulli Koester
(Institut Max von Laue-Paul Langevin (FR))
Co-authors
Prof.
Andreas Türler
(Paul Scherrer Institut)
Ms
Anna-Maria Rolle
(Universitätsklinik Tübingen)
Prof.
Bernd Pichler
(Universitätsklinik Tübingen)
Dr
Cristina Müller
(Paul Scherrer Institut)
Mr
Holger Dorrer
(Paul Scherrer Institut)
Mr
Jonathan Sakarias Siikanen
(Lund University)
Dr
Konstantin Zhernosekov
(Paul Scherrer Institut)
Prof.
Mikael Jensen
(Risø National Laboratory)
Prof.
Roger Schibli
(Paul Scherrer Institut)
Dr
Stefan Wiehr
(Universitätsklinik Tübingen)
