Conveners
Biophysics and Medical
- Klaus Blaum (Max-Planck-Gesellschaft (DE))
Thierry Stora
(CERN)
12/18/12, 11:10 AM
Invited
The ISOLDE facility at CERN is in operation for more than forty years, and has successfully extended various technological aspects of the so-called ISOL beam production, extracting high-purity grade exotic radioisotope beam “online”, while irradiating 20cm thick targets with about 50% of the available CERN 1.4 GeV protons. In its present location since 1991, the ISOLDE facility has delivered...
Dr
Cristina Müller
(Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland)
12/18/12, 11:40 AM
Submitted
Background: Compared to other lanthanides, terbium (Tb) comprises clinically attractive radionuclides such as 152Tb and 155Tb with suitable decay properties for PET and SPECT imaging and 149Tb and 161Tb suitable for targeted alpha- and beta-radionuclide therapy. To evaluate these 4 radioisotopes we employed the folic acid/folate receptor (FR)-targeting strategy which has been thoroughly...
Dr
Lars Hemmingsen
(Dept. of Natural Sciences, The Royal Veterinary and Agricultural University)
12/18/12, 12:00 PM
Submitted
Due to the complexity of systems in living matter nuclear techniques are not commonly used in biology and biochemistry. The ISOLDE facility is, however, a perfect place for carrying out experiments with Perturbed Angular Correlation of γ-rays (PAC) spectroscopy. This well established technique is suitable for addressing different biological topics, such as metalloprotein structure, dynamics of...
Dr
Alexander Gottberg
(CERN / CENBG / CSIC)
12/18/12, 12:20 PM
Submitted
In August 2012 β-NMR spectroscopy was successfully applied for the world’s first experiments on liquid samples - an achievement which opens new avenues of research in the fields of wet chemistry and biochemistry. This project was motivated by the need for finding a new experimental approach to directly study biologically highly relevant metal ions, such as: Mg(II), Cu(I), Ca(II), and Zn(II)....
