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New heavy particles that couple only to leptons may explain the observed discrepancy in the muon anomalous magnetic moment, g-2. I discuss how the LHC can probe such new particles in direct production. Leptophilic particles are also promising candidates of dark matter, since they evade constraints from scattering off nuclei. I show that LEP constraints from loop-induced four-lepton interactions are comparable or superior to mono-photon searches. At a future electron-positron collider, lepton interactions can reveal details about the scale and structure of dark sectors