Feb 15 – 19, 2016
Vienna University of Technology
Europe/Vienna timezone

Intraoperative probe for radioguided surgery with beta- decays in brain tumor resection

Feb 18, 2016, 3:15 PM
20m
EI9 (Vienna University of Technology)

EI9

Vienna University of Technology

Gusshausstraße 27-29, 1040 Wien
Talk Medical Applications Medical Applications

Speaker

Elena Solfaroli Camillocci (Sapienza)

Description

The radio-guided surgery (RGS) represents a very useful surgical adjunct to intraoperatively detect millimetric tumor residues, enabling a radical resection. The main innovation of the RGS exploiting beta- emitters is the lower target-to-background ratio compared to the established technique using gamma or beta+ radiation, that allows the extension of the RGS to further clinical cases. For feasibility studies on brain tumors we developed and tested prototypes of an intraoperative probe detecting beta- decays, the device core being a scintillator with high light yield, non-hygroscopic property and low density. Portable readout electronics with wireless data transfer to the PC has been customized to match the surgeon needs. Preclinical tests with dedicated phantoms and test on *ex-vivo* specimen showed very promising results for the RGS application on brain tumors. This presentation will discuss the innovative aspects of the method, the status of the intraoperative probe development, the preclinical tests and the first tests on *ex-vivo* specimen of patients affected by meningiomas.

Primary author

Co-authors

Andrea Russomando (Universita e INFN, Roma I (IT)) Carlo Mancini Terracciano (Universita e INFN, Roma I (IT)) Eleonora Capparella (Sapienza Universita' di Roma) Francesco Collamati (Sapienza Universita' di Roma) Giacomo Traini (Sapienza Universita' di Roma) Gianluca Ioannidis (Sapienza Universita' di Roma) Giulia LIMITI (ISS and Sapienza Universita' di Roma) Marco Toppi (INFN Laboratori Nazionali di Frascati) Michela Marafini (INFN Roma) Raffaella Donnarumma (Unknown) Riccardo Faccini (Sapienza Universita' di Roma) Silvio Morganti (Dipartim.di Fisica G.Marconi RomeI) Valerio Bocci (Universita e INFN, Roma I (IT))

Presentation materials