Two space telescopes are described: GLAST (Gamma-ray Large Area Telescope) and INSPIRE (INternational Spectro-Polarimetric Imaging x-Ray Explorer). GLAST is a pair convertion telescope based on a 80mq Silicon tracker and a CsI Electromagnetic calorimeter directly derived from the high energy experiments. GLAST will explore the uncovered energy spectrum from 30MeV to 1TeV. INSPIRE is a twin x-ray telescope. One optcis will be instrumented with an high resolution bolometric spectrometer. The second optic will be instrumented with a Micro-Pattern Gas Detector (MPGD) with unique polarimetric capabilities allowing for the first time the analysis of the polarization of the x-ray sources in the 1-10 KeV range.