Franco Garibaldi
(Sezione Sanita(ISS))
04/09/2009, 08:20
S Surti
(University of Pensilvania)
04/09/2009, 08:30
M Conti
(Siemens)
04/09/2009, 09:00
Franco Garibaldi
(Sezione Sanita(ISS))
04/09/2009, 09:30
Prostate cancer (PCa) is the sixth most common cancer in the world, the third most common cancer in men, and the most common cancer in men in Europe, North America, and some parts of Africa. The incidence is increasing steadily in almost all countries, yet we know little about its causes. PCa is a biologically heterogeneous disease for which a variety of treatment options are available but a...
William Moses
(Lawrence Berkeley National Laboratory)
04/09/2009, 11:00
C Piemont
(IRS, FBK, Trento)
04/09/2009, 12:00
P Finocciaro
(INFN-LNS)
04/09/2009, 15:30
T Szczesniak
(Soltan Institute of Nuclear Studies)
04/09/2009, 16:00
A Rivetti
(INFN Torino)
04/09/2009, 16:30
P Musico
(Genova university & INFN Genoa)
04/09/2009, 17:30
INFN will fund a 3 years R&D program to develop a TOF-PET prostate probe.
A lot of experiences can be found and used in all involved fields: light sensors,
scintillators, electronics.
A readout architecture will be presented, introducing the requirements
and discussing the implementation.
An ASIC (Application Specific Integrated Circuit) will be designed to obtain the
requested...
F Corsi
(Politecnico di Bari & INFN Bari)
04/09/2009, 17:55
A Rivetti
(INFN Torino)
04/09/2009, 18:20
Dr
Stan Majewski
(Department of Radiology, University of West Virginia),
William Moses
(Lawrence Berkeley National Laboratory)
04/09/2009, 19:00
Prof.
Franco Garibaldi
(istituto di sanita, dipertimento TESA &INFN-Roma1, Rome, Italy),
Giacomo Cuttone
(INFN-LNS),
Marie Alix Duval
(Laboratoire Imagerie et Modélisation en Neurobiologie et Cancérologie, Centre National de la Recherche Scientifique, Universités Paris VII and Paris XI),
Paul Lecoq
(CERN),
Velio Macellari
(TESA, ISS)
05/09/2009, 08:15
Dr
Philippe Jehenson
(DG- Research Health Directorate, European Commission)
05/09/2009, 08:40
FP7: structure and budget; short description of 4 Specific Programmes (aspects that could be of particular interest to this audience).
•where in FP7 are their topic(s) of interest to this audience considered: medical imaging (mainly HEALTH programme, including image-guided therapy; slightly in nano and ICT)
•what in imaging has been funded up to now in the FP7 Health programme (with short...
Dr
John N. Aarsvold
(Department of Radiology, Emory University & Nuclear Medicine Service, Atlanta Veterans Affairs Medical Center)
05/09/2009, 09:00
Development of technologies, techniques, and protocols that make a surgical procedure incorporating radioisotope imaging possible and successful requires significant understanding of the technologies, techniques, and protocols relevant to the surgical task, and of the patient management goals of the surgical procedure. With emphasis on the imaging component of integration of imaging into...
Dr
Lenka Vermeeren
(Department of Nuclear Medicine, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital)
05/09/2009, 09:30
Exact localization of radioactive sentinel nodes is requisite to provide accurate staging with lymphatic mapping. SPECT/CT can exactly localize sentinel nodes and is able to depict more sentinel nodes than conventional (planar) images. It especially adds relevant information in areas with a complex anatomy, like the head and neck region and in pelvic and retroperitoneal areas. A portable gamma...
Dr
Claudio Amanti
(Operative Unit Chirurgia Senologica, University of Rome Sapienza II)
05/09/2009, 10:00
Dr
John Prior
(Nuclear Medicine Department, CHUV University Hospital)
05/09/2009, 11:00
This presentation will give an overview of molecular imaging tools (nuclear, optical imaging) and their possible use in the operating room in guiding oncologic abdominal surgery. For instance, the role of surgery in metastatic/recurrent cancer is currently being redefined, as new diagnostic tools and treatments are available: metastasectomy and cytoreductive can be considered viable management...
Thomas Wendler
(Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar & Computer Aided Medical Procedures (CAMP) Faculty of Computer Science)
05/09/2009, 11:30
The combination of tracking systems and intraoperative nuclear probes has been proposed recently as a promising way of enabling 3D intraoperative nuclear imaging. The particular experience of freehand SPECT, where a low energy gamma probe served as nuclear probe, has shown the feasibility of this approach in initial pilot studies. In the process several issues have emerged to be considered due...
Dr
Williams Moses
(Lawrence Berkeley National Laboratory)
05/09/2009, 12:00
There are a variety of strategies that can be used to detect the emission of positron-emitting (PET) and single photon-emitting (SPECT) radionuclides. The ones used in conventional PET and SPECT cameras cannot be directly applied to intraoperative imaging probes, mostly because of their physical size. Many designs require shielding, which exacerbates the size limitations. This presentation...
Dr
Mark B Williams
(Department of Radiology, Department of Biomedical Engineering, Department of Physics University of Virginia)
05/09/2009, 15:30
Background: Lymph node metastasis is a strong predictor of melanoma-associated mortality. However, the false negative rate for sentinel lymph node biopsy (SLNBx) has been reported as high as 24%. Intra-operative mobile gamma camera (MGC) imaging may improve the accuracy of SLNBx. Methods: From 4/08-9/08, 20 patients undergoing SLNBx for melanoma were imaged with MGC. Participants underwent...
Dr
David Brasse
(IPHC, Université de Strasbourg, CNRS/IN2P3)
05/09/2009, 16:00
The sentinel lymph node procedure is now widely used in the staging of breast cancer patients. The “classic” procedure uses preoperative lymphoscintigraphy combined with blue-dye injection and peroperative dedicated instrumentation. These devices have already been implemented by several research groups using different detector materials such as semiconductors and inorganic scintillating...
Marie Alix Duval
(Laboratoire Imagerie et Modélisation en Neurobiologie et Cancérologie, Centre National de la Recherche Scientifique, Universités Paris VII and Paris XI)
05/09/2009, 16:30
In addition to intra-operative probes, compact gamma cameras are very attractive to provide more efficient radio-labelled tumors localization. We have developed a high resolution intra-operative imager, POCI (Per-Operative Compact Imager), who has following imaging performances at 140 keV Tc99m gamma energy: a) spatial resolution of 2.3 mm FWHM and b) corresponding detection efficiency of 10.7...
Dr
Carl Jackson
(SensL technologies Ltd),
Frans Kniest
(Saint-Gobain Crystals),
Stefano Gioia
(Metaltronica)
05/09/2009, 17:30
Pietro Muto
(Department of Nuclear Medicine - A.O.Monaldi)
05/09/2009, 17:45
Pre-operative planar scintigraphy and intra-operative probe detection have been performed in a variety of solid tumors in the last decade.
Actually the new nuclear medicine tool is to better localize sentinel node and discover deeply located ones in mediastinum , abdomen and pelvis .
Moreover, to improve anatomical information, hybrid imaging devices such as SPECT-CT and PET-CT , that...
Paolo Finocchiaro PhD
(Nazionale di Fisica Nucleare – Laboratori Nazionali del Sud,)
05/09/2009, 18:45
The Silicon PhotoMultiplier (SiPM) has recently come out as a very promising photodetector for many forthcoming applications. Its capability to detect and resolve single photons, along with its wonderful timing figure, small size, insensitivity to magnetic fields, low voltage operations, intrinsic protection from accidental exposure to ambient light, make it a strong candidate for many future...
Dr
Jose Benlloch
(Instituto de Física Corpuscular (IFIC), Nuevos edificios de Investigación Paterna)
05/09/2009, 19:09
In this talk, we summarize the advances in electronics (for SiPms and other relevant technologies) in the context of intraoperative imagers. Those advances involve mainly ASIC designs. Emphasis will be given to intraoperative imagers designed for “SPECT” pharmaceuticals such as Tc99m-labeled colloids (low energy, single-photon detection). Different approaches for the electronics will be...
Dr
Niels Harlaar
(Institute for Medical and Biological Imaging, Technical University Munich and Helmholtz Center and Department of Surgery and BioOptical Imaging Center Groningen, University Medical Center Groningen)
05/09/2009, 19:30
We have developed an advanced multi-spectral fluorescence real-time imaging platform for assessing in positive surgical margins, loco-regional metastases and overall physiological and molecular biomarkers intra-operatively. The approach utilizes fluorochromes with targeting specificity, advanced optical imaging instrumentation and algorithms that yield quantitative and sensitive fluorescence...
Dr
Michael Hofmann
(Institut für Nuklearmedizin und PET-Zentrum, Klinikum Hildesheim GmbH)
06/09/2009, 08:30
Dr
Jose Leston
(Service de Neurochirurgie, Hôpital Henri Mondor)
06/09/2009, 09:30
The survival outcome of a patient suffering from a glioma is directly linked to the complete surgical resection of the tumor. To help surgeons delineate precisely the boundaries of a tumor, we developed an intra-operative positron probe with gamma background rejection capability. The probe was designed to be directly coupled to the excision tool such that detection and removal of the...
Dr
Neals Clinthorne
(Department of Radiology, University of Michigan)
06/09/2009, 10:30
PET tracers such as C11-choline potentially provide the ability to distinguish aggressive lesions from those in which “watchful waiting” is a more appropriate course of action. Nevertheless, there remains much controversy regarding the role of PET in detecting and managing prostate cancer with mixed results in the literature depending on the clinical study. Surprisingly, few of these studies...
Dr
Giuseppe Boni
(Nuclear Medicìne Unit, Department of Oncology and Radiology, A.O.U. Pisa)
06/09/2009, 11:30
In the last ten years, the widespread use of minimally invasive thoracic surgical procedures has prompted the development of nuclear medicine techniques for the pre-operative imaging and intra-operative probe detection of pulmonary lesions and mediastinal sentinel and metastastic nodes.
Moreover, the introduction in clinical practice of hybrid imaging devices like SPET/CT and PET/CT has...
Dr
Chumy Nwogu
(Roswell Park Cancer Institute)
06/09/2009, 12:00
Radioguided techniques to enhance the effectiveness of various thoracic procedures are being reported with increasing frequency in the literature. This includes the localization of pulmonary nodules for thoracoscopic resection, sentinel lymph node mapping, and attempts to identify all lymphatic micrometastatic disease in lung cancer patients.
The radiotracers that have been used clinically...
Dr
Benjamin Welch
(Dilon Technologies)
06/09/2009, 15:30
Dr
Roberto Pani
(representing the INFN ECORAD collaboration, INFN Roma1, 2nd Faculty of Medicine, Department of Experimental Medicine, Sapienza University of Rome)
06/09/2009, 15:40
Over the last five years, INFN has been studying the potential of LaBr3:Ce scintillation crystals for nuclear medicine application. The continuous improvement of each generation of crystals has resulted in the fabrication of detectors with excellent imaging characteristics at 140 keV with detection efficiencies between 70 and 90%, with energy resolution of 7%, with intrinsic spatial...
Dr
Francesco Scopinaro
(University “Sapienza)
06/09/2009, 16:00
We worked with two models—1in2 and 4 in2 FOV—of high-resolution hand-held cameras (HRCs), to verify if a HRC shows advantages over an Anger camera (AC) plus common gamma probe (GP). Methods: 280 patients with T1 breast cancer were divided in two groups of 140—one studied with AC-GP, the other with HRC. Patients were age, body mass index, and tumour size matched. Results: HRC detected more...
Dr
Doron Kopelman
(Department of Surgery BHaEmek Medical Center & Faculty of Medicine Technion, Israel Institute of Technology)
06/09/2009, 16:30
Hypothesis: The ability to obtain detailed visual assessments of radio-labeled tissues intra-operatively is expected to improve localization and removal of such targets. We have tested the capacity of a newly developed portable gamma camera to precisely locate sentinel lymph nodes using an injected radiotracer contrast agent both in an animal model and a preliminary clinical study. Design:...
Dr
Douglas J. Wagenaar
(Director of Research, Gamma Medica-Ideas,)
06/09/2009, 17:00
Cadmium Zinc Telluride (CZT) for single-photon emission imaging applications has seen remarkable progress in recent years. CZT is a room-temperature semiconductor that is capable of excellent energy resolution and intrinsic spatial resolution (including depth-of-interaction) – making it versatile in spectroscopic and pinhole magnification configurations. CZT is used in cutting-edge...
Dr
Hannah W. Hazard
(Department of Surgery, West Virginia University)
06/09/2009, 18:00
Rapid advancements in the surgical resection of primary breast cancers have occurred in the last century. This evolution has maintained oncologic principles with significant aesthetic improvements. Breast conserving surgery implies the removal of the tumor with negative margins while preserving the breast. Positive margin rates after initial lumpectomy can be as high as 40% necessitating...
Patricia Judy
(Department of Biomedical Engineering, University of Virginia)
06/09/2009, 18:15
Currently, the majority of lumpectomy and excisional biopsy procedures involving non-palpable breast lesions are performed using the wire localization (WL) technique. We are investigating dual-modality surgical guidance as a means of overcoming many of the problems associated with wire localization. The technique uses a dual-modality (digital mammography and breast scintigraphy) breast imaging...
Dr
Steven Falen
(Northern California PET Imaging Center)
06/09/2009, 18:30
As PET/CT has become more common in clinical practice, we are seeing patients earlier for diagnosis and staging and more frequently for monitoring of therapy. Some of the PET positive recurrent lesions we identify are anatomically within normal limits on CT. High resolution positron emission mammography (PEM) is a more recent tool for evaluating breast cancer. The lesions we identify on PEM...
